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Malignant tumours of thyroid gland in children


Authors: B. Uhliarová 1,2;  G. Bugová 1;  M. Čiljaková 3;  A. Hajtman 1
Authors‘ workplace: Klinika otorinolaryngológie a chirurgie hlavy a krku, UK JLF a UN, Martinprednosta prof. MUDr. A. Hajtman, PhD. 1;  Oddelenie otorinolaryngológie, FNsP F. D. Roosevelta, Banská Bystrica primár MUDr. M. Švec3Klinika detí a dorastu, UK JLF a UN, Martin prednosta prof. MUDr. P. Bánovčin, CSc. 2
Published in: Čes-slov Pediat 2015; 70 (1): 14-19.
Category: Original Papers

Overview

Background:
Thyroid nodules are less common among children than among adults. In contrast, thyroid nodules are more often malignant in childhood than in adulthood: in children 26% of thyroid nodules are malignant, while in adults the corresponding value is 5–10%.

Methods:
The authors retrospectively analyzed the pediatric patients that were surgically treated for thyroid disease at the Department of ENT and Head and Neck Surgery CU JMF in Martin between 2006–2013. Incidence of malignant disease, indications for surgery and its complications were evaluated.

Results:
A total of 1745 patients were surgically treated for thyroid disease at the Department of Otorhinolaryngology, Head and Neck Surgery, Comenius University, Jessenius Faculty of Medicine, Teaching Hospital in Martin, Slovakia from the 1st of January 2006 to the 31st of December 2013. There were 125 patients (7%) in pediatric age goup. Malignant tumours were identified in 26 children (21%). Incidence of malignant tumours was significantly higher in younger children (below 10 years) (p=0.026). Solitary node of thyroid gland was the most often indication for surgery (69 children, 55%), that was caused by malignancy in 15 children (22%). Lymph node enlargement was first sign of malignant disease in 4 children. All children were treated surgically by total thyroidectomy. Lymphadenectomy of central and lateral neck compartment was performed in 28% of children. Postoperative hypocalcaemia was detected in 4 children. Unilateral transient palsy of laryngeal recurrent nerve was present in 1 child. Permanent complications of thyroid surgery were not observed.

Conclusion:
Total thyroidectomy is the method of choice in the treatment of malignant tumour of thyroid gland. It is a safe operation with a low incidence of complication. If the lymphatic nodes are affected, the dissection of lymphatic node is indicated.

Key words:
malignant tumour, thyroid gland, children, diagnosis, therapy


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Neonatology Paediatrics General practitioner for children and adolescents
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