Terminálne zlyhanie obličiek u detí na Slovensku
Epidemiológia z Európskej perspektívy

Czech version

Authors: G. Koľvek ¹; Z. Kizeková ²; M. Dluholucký ³; M. Antonyová ⁴; Ľ. Podracká ¹
Authors‘ workplace: 1. Klinika detí a dorastu lekárskej fakulty Univerzity P. J. Šafárika a Detskej fakultnej nemocnice, Košice prednosta prof. MUDr. Ľ. Podracká, CSc. ¹; 1. Detská klinika Univerzity Komenského a Detskej fakultnej nemocnice s poliklinikou, Bratislava prednosta doc. MUDr. O. Červeňová, PhD. ²; 2. Detská klinika SZU a Detskej fakultnej nemocnice s poliklinikou, Banská Bystrica prednosta prof. MUDr. K. Kralinský, PhD. ³; Klinika detí a dorastu Jeséniovej lekárskej fakulty a Univerzitnej nemocnice, Martin prednosta prof. MUDr. P. Bánovčin, CSc. ⁴
Published in: Čes-slov Pediat 2012; 67 (Suppl 1): 18-24.
Category: Original Papers

Overview

Introduction:
The population of children with end-stage renal disease (ESRD) is growing, but reliable epidemiological information on its occurrence is not easy to obtain. The aim of this study was to determine the epidemiology of renal replacement therapy (RRT) in children with ESRD in Slovakia; compare it with previously published data on Slovakia as well as data on neighbouring countries and to explore the aetiology of ESRD.

Methods:
The data on the occurrence of RRT were collected over the years 2003–2009. The incidence and prevalence was calculated per million age related population (pmarp) and per million total population (pmtp) respectively. The data were compared with two earlier Slovak studies and with European data from the European Society of Paediatric Nephrology.

Results:
The median annual incidence of RRT in children younger than 15 years was 6.6 pmarp (1.5 pmtp). The prevalence rate on 31st December 2009 was 24.1 pmarp. Differences between 2002 and 2009 (18.6 pmarp, 3.2 pmtp) were not statistically significant. The comparison with neighboring countries and with the European average shows no significant difference in incidence, while prevalence is significantly lower compared to neighboring Austria and some other (mostly western) European countries. The aetiology of ESRD mainly concerned congenital anomalies (34.6%) and cystic kidney diseases (19.2%).

Conclusion:
The trend in the incidence and the prevalence of RRT in Slovak children is slightly positive, but the differences between the last published study (2002) and present are not statistically significant. Compared with the European average, the prevalence of RRT was significantly lower.

Key words:
end-stage renal disease, incidence, prevalence, etiology

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