Darier Disease and Related Disorders
Authors:
Z. Plzáková 1; J. Štork 1; M. Šlajsová 1
Authors‘ workplace:
Dermatovenerologická klinika 1. LF UK a VFN, Praha
přednosta prof. MUDr. Jiří Štork, CSc.
1
Published in:
Čes-slov Derm, 85, 2010, No. 6, p. 309-316
Category:
Reviews (Continuing Medical Education)
Overview
Darier disease and Hailey-Hailey disease are autosomal dominant dermatoses caused by dysfunction of intracellular transport of Ca2+ ions leading to defects of keratinocyte adhesion followed by suprabasal acantholysis and dyskeratosis. Clinical lesions of various extent are usually worsened by influence of mechanical and thermal irritating factors. Etiopathogenesis of Grover disease has not been fully disclosed yet. Article reviews the typical and less common disease manifestations as well as contemporary therapeutic options.
Key words:
Darier disease – Hailey-Hailey disease – Grover disease – acantholytic dyskeratosis – Ca2+ ATPase – retinoids
Sources
1. ALEXANDRESCU, DT., DASANU, CA., FARZANMEHR, H. et al. Development of squamous cell carcinomas in Darier disease: a new model for skin carcinogenesis? Br J Dermatol, 2008, 159 (6), p. 1378–1380.
2. DAVIS, MD., DINNEEN, AM., LANDA, N. et al. Grover’s disease: clinicopathologic review of 72 cases. Mayo Clin Proc, 1999, 74 (3), p. 229–234.
3. HOHL, D., MAURO, T. Darier disease and Hailey-hailey disease. In BOLOGNA, JJ., JORIZZO, JL., RAPINI, RP. Dermatology. Spain: Mosby Elsevier, 2008, p. 791–800.
4. HURD, DS., JOHNSTON, C., BEVINS, A. A case of Hailey-Hailey disease treated with alefacept (Amevive®). Br J Dermatol, 2008, 158 (2), p. 399–401.
5. JACOBSEN, NJ., LYONS, I., HOOGENDOORN, B. et al. ATP2A2 mutations in Darier’s disease and their relationship to neuropsychiatric phenotypes. Hum Mol Genet, 1999, 8 (9), p. 1631–1636.
6. JULLIARD, KN., MILBURN, PB. Antibiotic ointment in the treatment of Grover disease. Cutis, 2007, 80 (1), p. 72–74.
7. KELLERMAYER, R., AIELLO, DP., MISETA, A. et al. Aminoglycosides as potential pharmacogenetic agents in the treatment of Hailey-Hailey disease. J Invest Dermatol, 2006, 126 (1), p. 229–231.
8. MELWANI, PM., PARSONS, AC., SANGUEZA, OP. Early histopatologic changes in Grover disease. Am J Dermatopathol, 2010, 32 (6), p. 565–567.
9. NARBUTT, J., LESIAK, A., ARKUSZEWSKA, C. et al. Effective treatment of recalcitrant Hailey-Hailey disease with electron beam radiotherapy. JEADV, 2007, 21 (4), p. 567–568.
10. RAJPARA, SM., KING, CM. Hailey-Hailey disease responsive to topical calcitriol. Br J Dermatol, 2005, 152 (4), p. 816–817.
11. RUBEGNI, P., POGGIALI, S., SBANO, P. et al. A case of Darier’s disease successfully treated with topical tacrolimus. JEADV, 2006, 20 (1), p. 84–87.
12. RUIZ-PEREZ, VI., CARTER, SA., HEALY, E. et al. ATP2A2 mutations in Dariers’s disease: variant cutaneous phenotypes are associated with missense mutations, but neuropsychiatric features are independent of mutation class. Hum Mol Genet, 1999, 8 (9), p. 1621–1630.
13. SCHMIDT, H., OCHSENDORF, FR., WOLTER M. et al. Topical 5-fluorouracil in Darier disease. Br J Dermatol, 2008, 158 (6), p. 1371–1401.
14. VAN’T WESTEINDE, SC., SANDERS, CJ., VAN WEELDEN, H. Photodynamic therapy in a patient with Darier’s disease. JEADV, 2006, 20 (7), p. 870–872.
15. VOSMÍK, F., KRAJSOVÁ, I.: Chronická benigní akantolytická dermatóza – varianta přechodné akantolytické dermatózy Groverovy. Čs. Derm, 1980, roč. 55, č. 5, s. 301–308.
16. WEAVER, JL., BERGFELD, WF. Grover Disease (Transient Acantholytic Dermatosis). Arch Pathol Lab Med, 2009, 133 (9), p. 1490–1494.
Labels
Dermatology & STDs Paediatric dermatology & STDsArticle was published in
Czech-Slovak Dermatology
2010 Issue 6
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