Non-invasive Screening Examination of GenitalChlamydiosis in Brno Adolescents

Czech version

Authors: L. Pospíšil ¹; R. Buček ⁴; I. Diblíková ¹; M. Dražďáková ²; Z. Medková ⁴; M. Pejčoch ⁵
Authors‘ workplace: Výzkumný ústav veterinárního lékařství Brno, ředitel prof. MVDr. K. Hruška, CSc. 2 Ústav klinické biochemie 1. LF UK a VFN, přednosta doc. MUDr. T. Zima, DrSc. 3 Zdravotní odbor Magistrátu města Brna, vedoucí MUDr. Z. Prosková 4 Bioplus, s. r. o., Brno, ř
Published in: Ceska Gynekol 2000; (6): 413-416
Category:

Overview

Objective:
To run a screening for genital chlamydiosis in adolescents living in the town Brno asthe first action of this type in the Czech Republic and to use the results of the screening for theelaboration of recommendations for running similar actions on the national scale.Design: Prospective epidemiological study.Setting: Veterinary Research Institute, Brno; Institute of Clinical Biochemistry, 1 st Faculty ofMedicine, Charles University and General Faculty Hospital, Prague; Section of Public Health,Municipal Authorities of Brno; Bioplus Ltd., Brno; Regional Hygienic Services, Brno; FacultyHospital Brno; with technical assistance of teachers and students of two Medical Assistant Schoolsin Brno.Methods: Students (337 females and 15 males) of two Medical Assistant Schools, older than 18years, were used as probands within the study. Sediments of the first portions of urine col lectedfrom the individual probands were tested for the presence of Chlamydia trachomatis using thedirect fluorescent test, ELISA, and the ligase chain reaction.Results: Positive reactions in any of the three tests were found in 31 of the 352 probands (8.8%).Positive and doubtful reactions in the direct fluorescent antibody test were obtained in 11 (35.5%)and 3 (9.6%) of the 31 reactors, respectively. The corresponding values for ELISA were 9 (23.0%)and 8 (25.8%), respectively, and those for the ligase chain reaction 3 (16.6%) and 3 (16.6%), respecti-vely. The overall prevalence of 8.8% is higher than the European mean.Conclusions: The first limited screening for genital Chlamydia infections in the Czech Republicwas run in Brno. Urinary samples were collected from 337 females and 15 males aged approxima-tely 18 years. The presence of Chlamydia trachomatis in the urinary sediment was demonstratedby the direct fluorescent test, ELISA, and the ligase chain reaction. The established prevalence of8.8% exceeded the European mean (3.9%).

Key words:
C. trachomatis, non-invasive screening

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