New pharmacotherapy of diabetes

Czech version

Authors: T. Edelsberger
Authors‘ workplace: Diabetologická ambulance, Krnov
Published in: Kardiol Rev Int Med 2014, 16(2): 138-142
Category: Internal Medicine

Overview

The article presents an overview of current and prospective pharmacological therapy of diabetes mellitus. New pathophysiological findings over the last decade have instigated efforts to find drugs that would be able to positively affect the newly discovered abnormalities in glucose metabolism and contribute to its impact on the treatment of diabetes. Some of these drugs, such as inhibitors of dipeptidyl peptidase 4 (DPP‑ 4) or glucagon‑like peptide 1 (GLP‑1) agonists, have been used successfully, and the others are waiting to be launched (SGLT‑ 2 inhibitor – dapagliflozin) or are undergoing different stages of clinical testing.

Keywords:
diabetes mellitus – antidiabetics – pharmacotherapy

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