Brno registr – has the post‑MI pharmacotherapy changed in recent years?

Overview

Brno registr – has the post‑MI pharmacotherapy changed in recent years? We provide an overview of pharmacotherapy of the patients discharged from the Teaching Hospital Brno in two consequent periods 2003–2004 and 2005–2008. The former data originate from a doctoral thesis and the latter are extracted from the Brno Register. The 2003–2004 data contain information on 884 patients with the mean age of 67 years; 95% of patients left the hospital with antiaggregation treatment and 73.9% were on combined antiaggregation treatment (ASA and thienopyridines). Pharmacotherapy of 89.2% of patients included a beta‑blocker, 85.8% of patients had an ACEI or sartan, 37.9% diuretics, 20% nitrates and 87.1% a hypolipidemic agent. The Brno Register provided data on 2005 acute myocardial infarctions (MI) in 1858 patients. 88 patients died during hospitalisation, 1917 patients were discharged for further care at home or another healthcare institution. At discharge, 89.15% of patients were prescribed an ACE inhibitor or an AII antagonist, 89.51% a beta‑blocker, 93.74% an antiaggregation treatment and 89.50% a hypolipidemic agent. All 4 treatment groups were prescribed to ¾ of patients and further 1/5 had at least 3 main groups according to the guidelines.

Keywords:
myocardial infarction – ACE inhibitor – beta-blocker – antiaggregation – statin