Borrelial pseudolymphoma of the eyebrow in an adult

Česká verze

Authors: Vlastimil Woznica ^1,2 ; Inka Třešková ^1,2
Authors place of work: Oddělení plastické chirurgie, Fakultní nemocnice Plzeň ¹; Univerzita Karlova, Lékařská fakulta Univerzity Karlovy v Plzni ²
Published in the journal: Rozhl. Chir., 2023, roč. 102, č. 2, s. 88-90.
Category: Kazuistika
doi: https://doi.org/10.33699/PIS.2023.102.2.88–90

Summary

Borrelial pseudolymphoma, more commonly known as Borrelia lymphocytoma and previously also as lymphadenosis benigna cutis, is a rare manifestation of Lyme borreliosis, which occurs nearly always in children after an infection caused by Borrelia afzelii; this pathogen is transmitted exclusively by the Ixodes ricinus tick in our region. The most common body locations of this lymphocytoma include the earlobe, scrotum, nipples and the areomamillary complex. Therefore, the case of our patient was unexpected and quite rare. The aim of this article is to point out the high incidence of Lyme disease and its atypical manifestations which can be cured without surgical intervention in most cases. The authors describe the case of a 58-year-old healthy female patient with a very rare manifestation of Lyme disease.

Keywords:

Ixodes – Lyme disease – Borrelia burgdorferi – pseudolymphoma – skin neoplasms

Zdroje

1. Glatz M, Resinger A, Semmelweis K, et al. Clinical spectrum of skin manifestations of lyme borreliosis in 204 children in Austria. Acta Derm Venerol. 2015;95(5):565–571. doi: 10.2340/00015555-2000.

2. Strnad M, Hönig V, Růžek D, et al. Europe- wide meta-analysis of Borrelia burgdorferi sensu lato prevalence in questing Ixodes ricinus ticks. Appl Environ Microbiol. 2017 Jul 17;83(15):e00609–00617. doi: 10.1128/AEM.00609-17.

3. Bobe JR, Jutras BL, Horn EJ, et al. Recent progress in Lyme disease and remaining challenges. Front Med. (Lausanne) 2021 Aug 18;8:666554. doi: 10.3389/ fmed.2021.666554.

4. Wallace D, Ratti V, Kodali A, et al. Effect of rising temperature on Lyme disease: Ixodes scapularis population dynamics and Borrelia burgdorferi transmission and prevalence. Can J Infect Dis Med Microbiol. 2019 Sep 16;2019:9817930. doi: 10.1155/2019/9817930.

5. Mullegger RR. Dermatological manifestations of Lyme borreliosis. Eur J Dermatol. 2004 Sep-Oct;14(5):296–309. PMID: 15358567.

6. Aucott JN, Seifter A, Rebman AW. Probable late Lyme disease: a variant manifestation of untreated Borrelia burgdorferi infection. BMC Infect Dis. 2012 Aug 1;12:173. doi: 10.1186/1471-2334-12-173.

7. Maraspin V, Nahtigal Klevišar M, Ružić-Sabljić E, et al. Borrelial lymphocytoma in adult patients. Clin Infect Dis. 2016 Oct 1;63(7):914–921. doi: 10.1093/cid/ciw417.

8. Lantos PM, Rumbaugh J, Bockenstedt LK, et al. Clinical practice guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis, and Treatment of Lyme Disease. Arthritis Rheumatol. 2021 Jan;73(1):12–20. doi: 10.1002/art.41562.

9. Arnež M, Ružić-Sabljić E. Borrelial lymphocytoma in children. Pediatr Infect Dis J. 2015 Dec;34(12):1319–1322. doi: 10.1097/INF.0000000000000884.

10. Miguel D, Peckruhn M, Elsner P. Treatment of cutaneous pseudolymphoma: A systematic review. Acta Derm Venereol. 2018 Mar 13;98(3):310–317. doi: 10.2340/00015555-2841.