Lymphatic System: Morphology and Pathology Update

Česká verze

Authors: I. Kholová
Authors place of work: Pathology, Laboratory Centre, Tampere University Hospital, Tampere, Finland
Published in the journal: Čes.-slov. Patol., 46, 2010, No. 4, p. 98-103
Category: Přehledový článek

Summary

The lymphatic system is crucial for the maintenance of tissue fluid balance, immune surveillance, and fatty acids absorption in the intestine. The lymphatic vessels are also involved in the pathogenesis of tumor metastasis, lymphedema, and various inflammatory processes. Recently, several markers specific for lymphatic endothelium were found. Progress in the field of lymphatic growth factors and their receptors, and molecular lymphatic biology has helped to understand better the lymphatic vasculature. This review summarizes the updates on lymphatic system research and possible applications in routine pathological diagnostics.

Key words:
lymphangiogenesis – lymphatic system

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