Pancreatic cancer screening: ready for prime time?

Česká verze

Authors: Vaněk P. ¹; Zoundjiekpon V. ¹; Slodička P. ¹; Tichý T. ¹; Tesaříková J. ²; Švébišová H. ³; Kovář R. ⁴; Kurfürstová D. ⁵; Janíková M. ⁶; Woitková V. ⁶; Procházka M. ⁶; Falt P. ¹; Urban O. ¹; Hepacas Výzkumnou Skupinu Za
Authors place of work: II. interní klinika – gastroenterologická a geriatrická LF UP a FN Olomouc ¹; I. chirurgická klinika LF UP a FN Olomouc ²; Onkologická klinika LF UP a FN Olomouc ³; Radiologická klinika LF UP a FN Olomouc ⁴; Ústav klinické a molekulární patologie LF UP a FN Olomouc ⁵; Ústav lékařské genetiky LF UP a FN Olomouc ⁶
Published in the journal: Gastroent Hepatol 2021; 75(5): 390-398
Category: Přehledová práce
doi: https://doi.org/10.48095/ccgh2021390

Summary

Early detection of pancreatic cancer is considered to be the most effective way to improve survival. Individuals with familial occurrence or genetic susceptibility syndromes have an increased risk of developing pancreatic cancer. Current guidelines are based on evidence of the benefits of systematic surveillance in high-risk individuals and emphasize the potential of screening programs to affect overall survival. This type of screening has not yet been introduced in the Czech Republic even though such programs are already being established in other countries. With this review we aim to summarize knowledge about hereditary and familial pancreatic cancer and issue a call for collaboration on a pilot screening program.

Keywords:

Cancer screening – Pancreatic cancer – hereditary pancreatic cancer

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