Search

News Doc. Tomáš Gabrhelík: Pain treatment should be seriously addressed by all fields, especially in seniors

Chronic pain is often underestimated, especially in older and polymorbid patients. On the other hand, during self-treatment, many patients use inappropriate medication for a long time. The treatment of prolonged and more intense pain should be managed by an algologist, and other specialists should not forget to monitor the patient's documentation to avoid medication duplication and other risks arising from inappropriate prescription. We discuss the pitfalls and benefits of analgesic treatment with doc. MUDr. Tomáš Gabrhelík, Ph.D., from the pain treatment clinic at the Department of Anesthesiology, Resuscitation, and Intensive Medicine at the Faculty of Medicine, Palacký University and University Hospital Olomouc.

Source: Analgesia 27. 9. 2023

Články časopisu Antibiotical prophylaxy in gynecology

Author of the article: J. Záhumenský, E. Menzlová, J. Zmrhal, E. Kučera Source: Česká gynekologie | 4/2013 9. 8. 2013

News SCOPE 2021 –⁠ State of Osteoporosis and Its Treatment in European Countries

The SCOPE 2021 project (The Scorecard for Osteoporosis in Europe) by the International Osteoporosis Foundation (IOF) gathered and tabulated data from 29 European countries on the burden of osteoporosis, the quality and availability of services related to the diagnosis and treatment of this disease, and the use of these services in individual states. Within the significantly heterogeneous results, the Czech Republic did not fare very well.

Source: Osteoporosis – Trends in Sequential Therapy 4. 9. 2023

News Magnetic Resonance Can Reduce the Need for Prostate Biopsies

As early as 2013, Czech experts demonstrated that in patients with elevated prostate-specific antigen (PSA) levels, imaging using a 3-Tesla magnetic resonance (3T MRI) can replace biopsy in many cases when detecting prostate cancer.

Source: Prostate Health Index 4. 6. 2020

News Efficacy and Safety of Preservative-Free Latanoprost in the Treatment of Open-Angle Glaucoma and Elevated Intraocular Pressure –⁠ Results of a Meta-Analysis

Many eye drops for the treatment of glaucoma still contain preservatives today. However, these can cause eye irritation, so non-preservative formulations should be preferred. The following meta-analysis compared the efficacy and safety of antiglaucoma medications with and without preservatives.

Source: Treatment of Glaucoma 14. 1. 2021

News Why Do Women in the USA Receive Indicated Statin Therapy Less and in Lower Doses Than Men?

Statin use has been proven to reduce the risk of cardiovascular diseases in both men and women. However, women in the USA who are indicated for this treatment have historically taken it less frequently and in lower doses than men. The current status and possible causes were investigated by the study presented below.

Source: Cardiovascular Risks 31. 1. 2020

News MUDr. Tomáš Mašek: In the prevention of hemorrhoids, more use of venopharmaceuticals is needed

While in the past the diagnosis of hemorrhoids was inextricably linked to traditional surgical solutions, today -⁠ thanks to the expansion of the indication for venopharmaceuticals for this condition -⁠ the number of patients who have to undergo these procedures is a minority. We asked coloproctologist MUDr. Tomáš Mašek how the potential of venopharmaceuticals can be utilized in the prevention and treatment of hemorrhoid disease.

Source: Venous Insufficiency 7. 11. 2023

News Inhibition of Mutated KRAS Protein as a New Option for Targeted Treatment of Non-Small Cell Lung Cancer

RAS proteins are molecular switches for several intracellular signaling pathways. Their dysfunction due to mutation leads to the development and progression of malignant diseases such as colon or lung cancers. At the beginning of 2022, the inhibitor of the mutated KRAS protein, sotorasib, was approved. The following article outlines the effect of this first representative of a new drug group and its potential in the treatment of non-small cell lung cancer (NSCLC).

Source: Lung Cancer 9. 11. 2023

News Current Indications for Negative Pressure Therapy in Wound Healing in Orthopedic and Traumatological Patients

Negative pressure wound therapy was introduced in North America in 1997. Since then, the method has gained great popularity and is used in the treatment of many acute and chronic wounds. Like any other treatment modality, it has its proper indications and contraindications. An overview article by French authors evaluates the current use of negative pressure therapy in the fields of orthopedics and trauma of the musculoskeletal system.

Source: Wound Healing 14. 6. 2022

News Changes in Intestinal Microflora Correlate with Disease Activity in Patients with Lupus Erythematosus

The role of intestinal microflora in the pathogenesis of autoimmune diseases, including lupus erythematosus, has been discussed for a long time. An American study discovered a specific bacterium whose proliferation in the intestine correlates not only with the occurrence of the disease but also with its activity.

Source: Arthritis 4. 2. 2020

News Options for Anticoagulant Therapy During Catheter Ablation for Atrial Fibrillation: Safety and Efficiency of Bridging with Dabigatran Compared to Interruption of NOACs

Catheter ablation is an established method for treating supraventricular and ventricular arrhythmias. Patients with atrial fibrillation should also use anticoagulant therapy to prevent thromboembolic events, even during ablation. The number of patients being treated with new anticoagulants (NOACs) is increasing, but the use of direct factor Xa inhibitors poses a risk of life-threatening bleeding during catheterization if a specific antidote is not available at the healthcare facility. Options to prevent this complication include short-term switching to dabigatran or complete interruption of NOACs therapy with temporary heparin support. The aim of the presented study was to compare the safety and feasibility of both methods.

Source: Anticoagulant Treatment 23. 6. 2020

News How to Navigate the Challenges of Anticoagulant Therapy in Pregnant Women −⁠ A Case Study

Every carrier of a mechanical heart valve is also on anticoagulant therapy. Warfarin is most commonly used for this purpose, but it is not suitable during pregnancy due to the risk of embryopathy. So how should we approach patients with artificial valves who wish to become pregnant? The following case study presents one option.

Source: Thromboprophylaxis 3. 1. 2024

News Cardio-renal-metabolic syndrome in context

The increase in the incidence of type 2 diabetes mellitus (T2DM), cardiovascular diseases (CVD), and chronic kidney disease (CKD) ranks among the most significant health issues of our time. Based on recent studies, these conditions are likely interconnected at various levels, whether in epidemiology, pathophysiology, or patient prognosis. Consequently, the term cardio-renal-metabolic syndrome (CRMS) has been defined.

Source: Heart Failure 16. 1. 2024

News Lurasidone in Antipsychotic Therapy –⁠ A Case Study of a Virtual Patient from the Laurie Project

MUDr. Elis Bartečků, Ph.D., from the Department of Psychiatry at MU LF and FN Brno presented the current possibilities of telemedical education at the XIV congress of the Psychiatric Society of the CLS JEP in Mikulov, specifically the so-called virtual patient within the interactive online Laurie project by Angelini Pharma. The presentation involved the case of a 20-year-old man with a severe psychotic disorder and equally severe somatic comorbidity.

Source: Modern Treatment of Schizophrenia 18. 8. 2022

News Prolonged Course of Metastatic Stomach Cancer with Long-term Stabilization –⁠ Case Report

In the following case report, we present the case of a patient with a prolonged oncological disease –⁠ stomach cancer. The patient has been asymptomatic for a long time and in good performance status despite multiple lung metastases, thanks to stabilization with trifluridine/tipiracil treatment.

Source: Treatment of Gastrointestinal Carcinomas 24. 5. 2022