Virulent profile and resistance of Escherichia coli isolated in immunocompromised patients with urosepsis
Authors:
M. Kmeťová; E. Kendrovská; V. Takáčová; M. Sabol; L. Siegfried
Published in:
Urol List 2012; 10(4): 37-40
Overview
We have been studying the characteristics of E. coli strains isolated from blood of immunocompromised patients suffering from urosepsis. In each patient (n = 25) a different strain has been tested. In the tested strains we have most often found gene adherence fimA (96%) and pap (56%). From the genes coding toxin production we have found cnf (20%), α-hly (16%), lt (12%), and st (8%) in our set of strains. The incidence of aer and iucC genes supporting the survival of E. coli in host extracellular space and associated with Fe2+ utilization was 84% and 80%, respectively. From the phylogenetic perspective the studied E. coli strains most often belon-ged to phylogenetic groups B2 and D (53% and 32%, respectively). The highest resistance against antibacterial agents we have found against trimethoprim/sulfamethoxazol and ciprofloxacin (32%) and against ampicillin/ /sulbaktam (20%). All the strains were sensitive to piperacillin/tazobactam, colistin, amikacin and meropenem.
Key words:
Escherichia coli - urosepsis - virulence - resistance - phylogenetic group
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Paediatric urologist UrologyArticle was published in
Urological Journal
2012 Issue 4
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