Treatment modalities of skeletal involvement in prostate cancer patients
Authors:
V. Vít
Authors‘ workplace:
Urologická klinika FN Brno
Published in:
Urol List 2009; 7(4): 27-30
Overview
The author deals with the issue of metastatic prostate cancer and treatment of bone dissemination, which significantly disrupts patient´s quality of life (mainly in the form of serious skeletal related events). Author evaluates the impact of bisfosfonates therapy (zoledronic acid in particular) on quality of life. Despite definite data recommending bisfosfonates therapy as an integral part of palliative treatment in patients with disseminated prostate carcinoma is their use in clinical practice very infrequent. The aim of this article is to present an overview of bisfosfonates therapy benefits in disseminated prostate cancer treatment and a body of recommendations based on EBM (Evidence Based Medicine), which may help to promote a wide-spread usage of bisfosfonates in clinical practice.
Key words:
prostate cancer, bone dissemination, bisfosfonates, zoledronic acid
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