Multiple lymph node plasmacytosis with monoclonal gammopathy – plasma cell neoplasm or indolent B-lymphoma?

Czech version

Authors: Z. Král ¹; Marta Krejčí ¹; L. Říhová ²; L. Křen ³; Z. Řehák ⁴; R. Koukalová ⁴; L. Pour ¹; M. Štork ¹; Martin Krejčí ¹; V. Sandecká ¹; Z. Čermáková ⁵; Z. Adam ¹
Authors‘ workplace: Interní hematologická a onkologická klinika LF MU a FN Brno ¹; Oddělení klinické hematologie, LF MU a FN Brno ²; Ústav patologie, LF MU a FN Brno ³; Oddělení nukleární medicíny, Masarykův onkologický ústav Brno ⁴; Oddělení klinické biochemie, LF MU a FN Brno ⁵
Published in: Transfuze Hematol. dnes,27, 2021, No. 3, p. 262-265.
Category: Case Report
doi: https://doi.org/10.48095/cctahd2021262

Overview

We describe the clinical course, diagnosis and therapy of a rare case of indolent plasma cell proliferation with multiple involvement of lymph nodes and monoclonal gammopathy. At first, a diagnosis of plasma cell neoplasm with generalised lymphadenopathy and without significant bone marrow infiltration was considered. However, repeated examination of the lymph nodes and bone marrow changed the diagnosis to indolent marginal zone B-cell lymphoma with plasmacytic differentiation was rather than extramedullary nodal plasmacytoma.

Keywords:

plasmacytoma – indolent lymphoma with plasmacytic differentiation

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Primář MUDr. Jiří Horák, 11. 6. 1936 – 21. 6. 2021

Article was published in

Transfusion and Haematology Today

2021 Issue 3