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Accidental Finding of a Malignancy during Surgery for Unusual Intestinal Obstruction in a Female Patient Following Kidney Transplantation


Authors: K. Houdek;  R. Šulc;  V. Třeška;  J. Moláček
Authors‘ workplace: Chirurgická klinika FN v Plzni, přednosta: prof. MUDr. V. Třeška, DrSc.
Published in: Rozhl. Chir., 2009, roč. 88, č. 4, s. 189-191.
Category: Monothematic special - Original

Overview

This case report of 62 years old woman observed and treated in Vascular surgery Dpt. of University Hospital in Pilsen because of small bowel obstruction may be an example of a malignant disease, which can occur after using immunosuppressive drugs.

The reason of the obstruction was strangulation of the small bowel in a peritoneal defect, which was made arteficialy as a treatment of posttransplant lymf-collection. We found signs of malignant disease in peritoneal cavity during the operation, that was verified by biopsy. The patient did not suffer from malignant disease before the transplantation. The origin of malignancy was probably ovarian tumor.

Key words:
transplantation – immunosuppression – hernia


Sources

1. Popov, Z., Ivanovski, O., Kolevski, P., Stankov, O., Petrovski, D., Cakalaroski, K., Ivanovski, N. De novo malignancies after renal transplantation – a single-center experience in the Balkans; doi:10.1016/j.transproceed.2007.08.022

2. Fung, J. J., Jain, A., Kwak, E. J., Kusne, S., Dvorchik, I., Eghtesad, B. De novo malignancies after liver transplantation: A major cause of late death. Liver Transplantation, Vol. 1, No. 11, Suppl. 1, 2001.

3. Amado, A. Cancer incidence after immunosuppressive treatment following kidney transplantation. Critical Reviews in Oncology/Hematology, 56, 2005.

4. Baccarani, U., Adani, G. L., Mantanaro, D., Risaliti, A., Lorenzin, D., Avellini, C., Tilissi, P., Groppuzzo, M., Curro, G., Luvisetto, F., Beltrami, A., Bresadola, V., Viale, P. L., Bresadola, F. De novo malignancies after kidney and liver transplantation: Experience on 582 consecutive cases; doi:10.1016/j.transproceed.2006.02.016

5. Adani, G. L., Baccarani, U., Lorenyin, D., Gropuzzo, M., Tulissi, P., Montanaro, D., Curro, G., Sainz, M., Risaliti, A., Bresadola, V., Bresadola, F. De novo gastrointestinal tumours after renal transplantation: Role of CMV and EBV viruses. Clin. Transplant., 2006: 20.

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Surgery Orthopaedics Trauma surgery
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