Laryngeal chondrosarcoma: diagnosis, differential diagnosis, and treatment – case studies

Czech version

Authors: D. Ugorová ¹; M. Rosoľanka ¹; E. Tedlová ²; P. Vereš ³; M. Tedla ¹
Authors‘ workplace: Klinika otorinolaryngológie a chirurgie hlavy a krku LF UK a UN Bratislava ¹; Klinika pneumológie a ftizeológie LF UK a UN Bratislava ²; Medicyt s. r. o., Bratislava ³
Published in: Otorinolaryngol Foniatr, 74, 2025, No. 1, pp. 65-70.
Category: Case Reports
doi: https://doi.org/10.48095/ccorl202565

Overview

Laryngeal chondrosarcoma (LC) is a rare disease, accounting for 0.2% of all laryngeal malignancies and approximately 3% of all chondrosarcomas. Histological diagnosis is crucial as most laryngeal chondrosarcomas are low-grade and differentiation from benign chondroma is difficult. The growth of LC is slow with a late onset of symptoms. It is a radio-resistant type of tumor, hence why surgical resection is the first choice of treatment. The extent of resection depends on the histopathological grade, growth rate, and recurrence with consideration of future quality of life. The prognosis for low-differentiated LC is good with a very low risk of distant metastasis. We present the cases of 62and 68-year-old patients with low-grade chondrosarcoma of the annular cartilage with two different growth patterns who underwent debulking (case report 1) and total laryngectomy (case report 2).

Keywords:

Larynx – chondrosarcoma – treatment – cricoid cartilage

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