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The value of FDG PET/CT in the thromboembolic disease: review of the literature


Authors: David Zogala
Authors‘ workplace: Ústav nukleární medicíny, 1. lékařská fakulta Univerzity Karlovy a Všeobecná fakultní nemocnice v Praze, ČR
Published in: NuklMed 2020;9:42-48
Category: Review Article

Overview

The positron emission tomography combined with computed tomography (PET/CT) is a well established imaging modality in the oncological practice. The most frequently used radiopharmaceutical is 2-deoxy-2-(18F)fluoro-D-glucose (FDG). Due to the unspecific nature of its biodistribution it can also be used in the diagnosis of other clinical entities with increased metabolic turnover, especially in the inflammation and infection. Thromboembolic disease represents a relatively frequent and serious medical issue. Inflammatory and other hypermetabolic processes have substantial impact on its development. FDG PET/CT is not routinely used for its diagnosis, however direct or indirect signs of thromboembolic disease can be frequently encountered in the routine practice of PET/CT interpretation. This is a literature review analysing the role of FDG PET/CT in the primary diagnosis of thromboembolic disease, in the pulmonary hypertension evaluation, in the detection of the cause of unprovoked thromboembolic events and in the differentiation of tumor thrombus.

Keywords:

PET – Pulmonary hypertension – PET/CT – Positron emission tomography – thromboembolic disease – venous thrombosis


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