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Spine metastasis of malignant melanoma detected by SPECT/CT on gallium scintigraphy


Authors: Otto Lang 1;  Martin Krbec 2
Authors‘ workplace: Klinika nukleární medicíny, Universita Karlova, 3. LF a FN Královské Vinohrady, Praha 1;  Ortopedicko-traumatologická klinika, Universita Karlova, 3. LF a FN Královské Vinohrady, Praha 2
Published in: NuklMed 2013;2:71-75
Category: Casuistry

Overview

A case report of 67-y-old men with cancer duplicity is presented. He suffered from prostate cancer from 2009 and from malignant melanoma on his back with a positive sentinel node from May 2010. He was treated with chemo-radiotherapy for both diseases; he was clinically stable without signs of generalization. He was evaluated with gallium scan due to malignant melanoma in August 2010 and in June 2011 in our department. Both examinations were interpreted as negative. Back pain started in February 2013, CT scan detected compression of Th9 due to metastatic infiltration. Tissue specimen withdrawn during spine stabilization in April 2013 confirmed metastasis of amelanotic malignant melanoma. Revision of gallium scans proved increased accumulation of 67Ga citrate in Th9 on the examination in June 2011 comparing to that in August 2010. The detection was made possible thanks to fusion of scintigraphic SPECT images with low-dose CT.

Key words:
malignant melanoma, spine metastasis, gallium scan, SPECT/CT


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