Liver transplantation in patients with portal vein thrombosis
Authors:
Libor Janoušek 1; Miloš Adamec 1; Martin Oliverius 1; Pavel Trunečka 2; Miloš Kučera 1
Authors‘ workplace:
Institut klinické a experimentální medicíny Praha, Klinika transplantační chirurgie
1; Institut klinické a experimentální medicíny Praha, Transplantcentrum
2
Published in:
Čas. Lék. čes. 2011; 150: 72-74
Category:
Original Article
Overview
Background:
Portal vein thrombosis has (PVT) long been an absolute contraindication to liver transplantation. In patients scheduled for liver transplantation, portal vein thrombosis occurs in 4–15%.
Methods and results:
The authors retrospectively collected data on 740 patients who underwent an initial orthotopic liver transplant at the authors’ institution between 1996 and 2009. Mean follow-up was from 1 day to 6 years. There were 437 male patients and 303 female patients. We have performed this procedure in 57 recipients with PVT; this constitutes 7.7% of the overall transplant population. There was a 10.5% incidence of liver graft dysfunction, 10.5% of hepatic artery thrombosis, 19.3% of acute rejection and 17.5% of biliary complications. The overall incidence of relaparotomy for bleeding was 28% (16 patients). In-hospital mortality and late mortality were 15.8% and 31.6%, respectively. Volumes transfused were 17.1 (0–425) transfusion units of red blood cell, 27.1 (0–132) of fresh-frozen plasma and 2.6 (0–20) of platelets respectively.
Conclusions:
We confirm that PVT is not a contraindication to LTx at the present time.
Key words:
portal vein thrombosis, liver transplantation.
Sources
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Journal of Czech Physicians
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