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Recurrent urinary tract infections in kidney transplant patients with polycystic kidneys


Authors: Marcel Čellár 1;  Martina Konko Ová 1;  Eva Lacková 1;  Terézia Hrubá 2;  Peter Galajda 3;  Ivana Dedinská
Authors‘ workplace: II. interná klinika, Slovenská zdravotnícka univerzita, Nefrologicko‑transplantačné oddelenie, Fakultná nemocnica s poliklinikou F. D. Roosevelta, Banská Bystrica 1;  Oddelenie rádiológie, Fakultná nemocnica s poliklinikou F. D. Roosevelta, Banská Bystrica 2;  I. interná klinika, Univerzitná nemocnica Martin a Jesseniova lekárska fakulta Univerzity Komenského 3;  Transplantačné centrum a I. interná klinika, Univerzitná nemocnica Martin a Jesseniova lekárska fakulta Univerzity Komenského 4
Published in: Vnitř Lék 2022; 68(E-4): 4-9
Category: Original Contributions

Overview

Introduction: Kidney transplantation is now a routine method used to treat end-stage renal disease. About 10 % of kidney transplant patients are patients with autosomal dominant polycystic kidney disease (ADPKD). After successful kidney transplantation, recurrent urinary tract infections also occur in initially asymptomatic patients.

Material and methods: The group included 320 patients after kidney transplantation. We compared patients with ADPKD versus patients without ADPKD in terms of the presence of recurrent urinary tract infections.

The results: The incidence of recurrent urinary tract infections (rIMCs) was 18% in patients without ADPKD and 48% in patients without ADPKD. Nephrectomy after kidney transplantation due to recurrent urinary tract infections eliminated this infectious complication (in 86% of patients).

Conclusion: Kidney transplant patients with ADPKD have a significantly higher incidence of recurrent urinary tract infections. Removal of polycystic kidneys is a suitable solution if the infection persists.

Keywords:

kidneys – Transplantation – recurrent urinary tract infection – polycystic kidneys – ADPKD


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