Pioglitazone

Czech version

Authors: David Karásek
Authors‘ workplace: III. Interní klinika – nefrologická, revmatologická a endokrinologická, LF UP a FN Olomouc
Published in: Vnitř Lék 2020; 66(2): 121-125
Category:

Overview

Pioglitazone belongs to the drugs primarily reducing insulin resistance. Currently, it is the only insulin sensitizer available. In addition to hypoglycaemic action, it has a number of other metabolically beneficial effects that are responsible for its positive effect on the vascular wall. The paper provides an overview of cardiovascular clinical trials with pioglitazone, its safety profile and practical recommendations for its administration.

Keywords:

diabetes – pioglitazone – insulin resistance – heart failure – cardiovascular disease – Bladder cancer

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