Pharmacologically induced thyreopathy in patients with cardiovascular disease

Czech version

Authors: Tomáš Brutvan; Jan Krátký; Jana Ježková
Authors‘ workplace: III. interní klinika – endokrinologie a metabolismu 1. LF UK a VFN v Praze
Published in: Vnitř Lék 2019; 65(12): 802-808
Category:

Overview

Thyroid gland function is mediated by thyreoideal hormones, in which iodine is very important structural part. High iodine intake, can initiate thyroid dysfunction. Amiodarone induced hypothyroidism is treated with levothyroxine and amiodarone taking is not interrupted. Amiodarone induced hyperthyroidism is divided into two subtypes, which differ by mechanism of origin and treatment strategy. In patients with cardiovascular disease is higher possibility of getting substances, with high content of iodine in diagnostic-therapeutic examination with contrast or treatment with amiodarone. In this group of patients is necessary to control thyroid function regularly and to hold preventive actions.

Keywords:

hyperthyroidism – amiodarone – Hypothyroidism – Iodine – thyroid dysfunction

Sources

Marek J, Hána V (eds). Endokrinologie. Galén: Praha 2017. ISBN 978–80–7262–484–3.
Wolff J, Chaikoff IL. Plasma inorganic iodide as a homeostatic regulator of thyroid function. J Biol Chem 1948; 174(2): 555–564.
Reiners C, Wegscheider K, Schicha H et al. Prevalence of thyroid disorders in the working population of Germany: ultrasonography screening in 96,278 unselected employees. Thyroid 2004; 14(11): 926–932. Dostupné z DOI: <http://dx.doi.org/10.1089/thy.2004.14.926>.
O‘Brien T, Dinneen SF, O‘Brien PC et al. Hyperlipidemia in patients with primary and secondary hypothyroidism. Mayo Clin Proc 1993; 68(9): 860–866. Dostupné z DOI: <http://dx.doi.org/10.1016/s0025–6196(12)60694–6>.
Frost L, Vestergaard P, Mosekilde L. Hyperthyroidism and risk of atrial fibrillation or flutter: a population-based study. Arch Intern Med 2004; 164(15): 1675–1678. Dostupné z DOI: <http://dx.doi.org/10.1001/archinte.164.15.1675>. Erratum in Arch Intern Med 2005; 165(3): 307.
Stern RA, Robinson B, Thorner AR et al. A survey study of neuropsychiatric complaints in patients with Graves‘ disease. J Neuropsychiatry Clin Neurosci 1996; 8(2): 181–185. Dostupné z DOI: <http://dx.doi.org/10.1176/jnp.8.2.181>.
Dai G, Levy O, Carrasco N. Cloning and characterization of the thyroid iodide transporter. Nature 1996; 379(6564): 458–460. Dostupné z DOI: <http://dx.doi.org/10.1038/379458a0>.
Eng PH, Cardona GR, Fang SL et al. Escape from the acute Wolff-Chaikoff effect is associated with a decrease in thyroid sodium/iodide symporter messenger ribonucleic acid and protein. Endocrinology 1999; 140(8): 3404–3410. Dostupné z DOI: <http://dx.doi.org/10.1210/endo.140.8.6893>.
Saberi M, Utiger RD. Augmentation of thyrotropin responses to thyrotropinreleasing hormone following small decreases in serum thyroid hormone concentrations. J Clin Endocrinol Metab 1975; 40(3): 435–441. Dostupné z DOI: <http://dx.doi.org/10.1210/jcem-40–3-435>.
Markou KB, Paraskevopoulou P, Karaiskos KS et al. Hyperthyrotropinemia during iodide administration in normal children and in children born with neonatal transient hypothyroidism. J Clin Endocrinol Metab 2003; 88(2): 617–621. Dostupné z DOI: <http://dx.doi.org/10.1210/jc.2002–020681>.
Braverman LE. Iodine and the thyroid: 33 years of study. Thyroid 1994; 4(3): 351–356. Dostupné z DOI: <http://dx.doi.org/10.1089/thy.1994.4.351>.
Gartner W, Weissel M. Do iodine-containing contrast media induce clinically relevant changes in thyroid function parameters of euthyroid patients within the first week? Thyroid 2004; 14(7): 521–524. Dostupné z DOI: <http://dx.doi.org/10.1089/1050725041517075>.
Roti E, Uberti ED. Iodine excess and hyperthyroidism. Thyroid 2001; 11(5): 493–500. Dostupné z DOI: <http://dx.doi.org/10.1089/105072501300176453>.
Stanbury JB, Ermans AE, Bourdoux P et al. Iodine-induced hyperthyroidism: occurrence and epidemiology. Thyroid 1998; 8(1): 83–100. Dostupné z DOI: <http://dx.doi.org/10.1089/thy.1998.8.83>.
Rao RH, McCready VR, Spathis GS. Iodine kinetic studies during amiodarone treatment. J Clin Endocrinol Metab 1986; 62(3): 563–568. Dostupné z DOI: <http://dx.doi.org/10.1210/jcem-62–3-563>.
Franklyn JA, Davis JR, Gammage MD et al. Amiodarone and thyroid hormone action. Clin Endocrinol (Oxf) 1985; 22(3): 257–264. Dostupné z DOI: <http://dx.doi.org/10.1111/j.1365–2265.1985.tb03238.x>.
Fradkin JE, Wolff J. Iodide-induced thyrotoxicosis. Medicine (Baltimore) 1983; 62(1): 1–20. Dostupné z DOI: <http://dx.doi.org/10.1097/00005792–198301000–00001>.
Lambert M, Unger J, De Nayer P et al. Amiodarone-induced thyrotoxicosis suggestive ofthyroid damage. J Endocrinol Invest 1990; 13(6): 527–530. Dostupné z DOI: <http://dx.doi.org/10.1007/bf03348618
Bartalena L, Grasso L, Brogioni S et al. Serum interleukin-6 in amiodarone-induced thyrotoxicosis. J Clin Endocrinol Metab 1994; 78(2): 423–427. Dostupné z DOI: <http://dx.doi.org/10.1210/jcem.78.2.8106631>.
Brennan MD, Erickson DZ, Carney JA et al. Nongoitrous (type I) amiodaroneassociated thyrotoxicosis: evidence of follicular disruption in vitro and in vivo. Thyroid 1995; 5(3): 177–183. Dostupné z DOI: <http://dx.doi.org/10.1089/thy.1995.5.177>.
Smith TJ, Bahn RS, Gorman CA. Connective tissue, glycosaminoglycans, and diseases of the thyroid. Endocr Rev 1989; 10(3): 366–391. Dostupné z DOI: <http://dx.doi.org/10.1210/edrv-10–3-366>.
Dillmann WH. Biochemical basis of thyroid hormone action in the heart. Am J Med 1990; 88(6): 626–630. Dostupné z DOI: <http://dx.doi.org/10.1016/0002–9343(90)90530-q>.
Padovani RP et al. One month is sufficient for urinary iodine to return to its baseline value after the use of water-soluble iodinated contrast agents in post-thyroidectomy patients requiring radioiodine therapy. Thyroid 2012; 22: 926–930. Dostupné z DOI: <http://dx.doi.org/10.1089/thy.2012.0099>.
Goldschlager N, Epstein AE, Naccarelli GV et al. A practical guide for clinicians who treat patients with amiodarone: 2007. Heart Rhythm 2007; 4(9): 1250–1259. Dostupné z DOI: <http://dx.doi.org/10.1016/j.hrthm.2007.07.020>.
Connolly SJ. Evidence-based analysis of amiodarone efficacy and safety. Circulation 1999; 100(19): 2025. Dostupné z DOI: <http://dx.doi.org/10.1161/01.cir.100.19.2025>.
Rhee CM, Bhan I, Alexander EK et al. Association between iodinated contrast media exposure and incident hyperthyroidism and hypothyroidism. Arch Intern Med. 2012; 172(2): 153–159. Dostupné z DOI: <http://dx.doi.org/10.1001/archinternmed.2011.677>.
Nimmons GL, Funk GF, Graham MM et al. Urinary iodine excretion after contrast computed tomography scan: implications for radioactive iodine use. JAMA Otolaryngol Head Neck Surg 2013; 139(5): 479–482. Dostupné z DOI: <http://dx.doi.org/10.1001/jamaoto.2013.2552>.