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proLékaře.cz / Journals / Internal Medicine / 2019 - 1

Non-celiac gluten/wheat sensitivity: still more questions than answers

Czech version

Authors: Iva Hoffmanová
Authors‘ workplace: II. interní klinika 3. LF UK a FN Královské Vinohrady, Praha
Published in: Vnitř Lék 2019; 65(1): 19-23
Category:

Overview

Non-celiac gluten/wheat sensitivity (NCG/WS) is a syndrome characterized by intestinal and extra-intestinal sym­ptoms elicited by gluten/wheat ingestion in the persons, who are not affected by celiac disease and wheat allergy. Due to the lack of established biomarkers, the diagnosis of NCG/WS is based on the clinical picture, and it is necessary to validate it in well-defined double-blind, placebo-controlled challenge (The Salerno Experts´ Criteria). In the article is discussed a current knowledge of NCG/WS in terms of pathogenesis, diagnosis and treatment.

Key words:

gluten – gluten-related disorders – non-celiac gluten/wheat sensitivity – wheat

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