ScreenPro FH – projekt v oblasti screeningu zaměřený na familiární hypercholesterolemii ve střední, jižní a východní Evropě: odůvodnění a záměr
Authors:
Richard Češka 1; György Paragh 2; Željko Reiner 3; Maciej Banach 4; Lale Tokgözoğlu 5; Andrey; V. Susekov 6; Katarína Rašlová 7; Tomáš Freiberger 8,9; Branislav Vohnout 7,10; Andrzej Rynkiewicz 11; Assen Goudev 12; Gheorghe-Andrei Dan 13; Dan Gaiţă 14; Belma Pojskić 15; Ivan Pećin 3; Meral Kayıkçıoğlu 16; Olena Mitchenko 17; Marat V. Ezhov 18; Gustavs Latkovskis 19; Žaneta Petrulionienė 20; Zlatko Fras 21; Nebojsa Tasić 22; Erkin M. Mirrakhimov 23; Tolkun Murataliev 23; Alexander B. Shek 24; Vladimír Tuka 1; Alexandros D. Tselepis 25; Elie M. Moubarak 26; Khalid Al Rasadi 27
Authors‘ workplace:
Paul Stradins Clinical University Hospital, Riga, Latvia
; Third Department of Medicine – Department of Endocrinology and Metabolism of the First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
1; Institute of Internal Medicine, University of Debrecen Faculty of Medicine, Debrecen, Hungary
2; Department of Internal Medicine, Division of Metabolic Diseases, School of Medicine University of Zagreb, University Hospital Centre Zagreb, Zagreb, Croatia
3; Department of Hypertension, Medical University of Lodz, Lodz, Poland
4; Department of Cardiology, Hacettepe University Faculty of Medicine, Ankara, Turkey
5; Department of clinical Pharmacology and therapeutics, Academy for Postgraduate Education, Ministry of Health, Russian Federation
6; Coordination Centre for Familial Hyperlipidemias, Slovak Medical University, Bratislava, Slovakia
7; Molecular Genetics Lab, Centre for Cardiovascular Surgery and Transplantation, Brno, Czech Republic
8; Medical Faculty, Masaryk University, Brno, Czech Republic
9; Institute of Nutrition, FOaZOS, Slovak Medical University, Bratislava, Slovakia
10; Department of Cardiology and Cardiosurgery, Faculty of Medical Sciences, University of Warmia and Mazury, Olsztyn, Poland
11; Queen Giovanna University Hospital, Sofia, Bulgaria
12; University of Medicine Carol Davila, Colentina University Hospital, Bucharest, Romania
13; University of Medicine & Pharmacy Victor Babes, Institute of Cardiovascular Diseases, CardioPrevent Foundation Timisoara, Romania
14; Cantonal hospital, Zenica, Bosnia and Herzegovina
15; Cardiology Department, Ege University Medical School, Lipid Clinic, Izmir, Turkey
16; Institute of Cardiology, AMS Ukraine Dyslipidemia Department, Kiev, Ukraine
17; Russian Cardiology Research and Production Centre, Moscow, Russian Federation
18; Latvian Institute of Cardiology and Regenerative Medicine, Faculty of Medicine, University of Latvia
19; Centre of Cardiology and Angiology, Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania
20; Division of Internal Medicine, Preventive Cardiology Unit and Medical Faculty, University of Ljubljana, University Medical Centre, Ljubljana, Slovenia
21; Cardiovascular Research Centre, Cardiovascular Institute “Dedinje”, Belgrade, Serbia
22; National Centre of Cardiology and Therapy named after academician Mirsaid Mirrakhimov, Kyrgyz State Medical Academy naved after I. K. Akhunbaev, Bishkek, Kyrgyzstan
23; Republican Specialized Centre of Cardiology, Tashkent, Uzbekistan
24; Department of Chemistry, University of Ioannina, Atherothrombosis Research Centre, Ioannina, Greece
25; LDL apheresis Centre, Dahr El Bachek Government University Hospital – DGUH, Roumieh – Lebanon
26; College of Medicine and Health Science at Sultan Qaboos University, Sultan Qaboos University Hospital, Muscat, Oman
27
Published in:
Vnitř Lék 2017; 63(1): 43-48
Category:
Reviews
Overview
Familiární hypercholesterolemie (FH) je geneticky podmíněné onemocnění s velmi dobře popsaným genetickým přenosem a klinickým průběhem. I přes významný pokrok v nedávné době je familiární hypercholesterolemie dosud podceňovaná, nedostatečně diagnostikovaná a tedy i nedostatečně léčená. Jako společný rizikový faktor předčasného vzniku kardiovaskulárního onemocnění navíc představuje důležitou výzvu v oblasti zdravotní péče. Projekt ScreenPro FH je zaměřen na rozvoj mezinárodní sítě, která podpoří zkvalitňování komplexní péče – od včasného screeningu přes stanovení diagnózy až k nejmodernější léčbě familiární hypercholesterolemie ve střední, východní a jižní Evropě. Důležitým úkolem projektu je harmonizovat a sjednotit diagnostické a terapeutické přístupy v jednotlivých zúčastněných zemích, v nichž je situace v každé z nich odlišná. Země s většími zkušenostmi by měly sloužit jako vzor pro ty, které svou síť FH nyní budují.
Klíčová slova:
familiární hypercholesterolemie – screening – diagnóza – optimalizace léčby
Sources
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