Vitamin D – old substance in new perspectives

Czech version

Authors: Vladimír Kojecký
Authors‘ workplace: Interní klinika, Krajská nemocnice T. Bati, a. s., Zlín, přednosta MUDr. Jiří Latta
Published in: Vnitř Lék 2015; 61(7-8): 695-697
Category: Vanýsek´s day 2015

Overview

Receptors for vitamin D are present almost in all body tissues. Vitamin D does not only act as a regulator of calcium and phosphorus metabolism, but also a substance which modulates the immunity system function, regulates cell proliferation. Genetic, epidemiological and experimental data indicate a possible role of vitamin D deficiency in the development of some diseases, mainly of autoimmune diseases and tumours. The benefit of curative intake of vitamin D has so far not been proven. There is no reason why the deficiency of vitamin D should not be covered. The substitution should start with the replenishment of the lacking amount of vitamin D (which may even be several hundred thousand units) and involve ongoing intake of the recommended substitution dose of 800–1 000 vitamin D units per day.

Key words:
autoimmune disease – vitamin D – intestinal inflammation

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