Transplantation of haematopoietic cells and its role in the treatment of haematopoiesis during the last 25 years

Czech version

Authors: A. Vítek; M. Lukášová; V. Chudomel†; A. Májský†; J. Souček; P. Kobylka; P. Kořínková; M. Loudová; M. Dobrovolná; E. Matějková; M. Písačka; Z. Sieglová; M. Vraná; J. Hrabánek; J. Sajdová; D. Šponerová; M. Marková; V. Válková; Z. Gašová; P. Cetkovský
Authors‘ workplace: Ústav hematologie a krevní transfuze Praha, ředitel prof. MUDr. Marek Trněný, CSc.
Published in: Vnitř Lék 2012; 58(Suppl 2): 46-55
Category:

Overview

Haematopoietic cell transplantation is a life-saving procedure in a number of haematological diseases. Development of transplantation dates back to 1970s, following discovery of the HLA system. The Institute of Haematology and Blood Transfusion in Prague had initiated its transplantation programme in 1986 and 918 haematopoietic cell transplantations were performed for various haematological diseases until 2011. Long-term survival of all patients after transplantation is around 50%, ranging from 20 to 90%, depending on the type of the disease and its stage, the type of a donor and the patient’s age.

Key words:
haematopoietic stem cell transplantation – history of transplantation– transplantation in acute myeloid leukaemia – transplantation in chronic myeloid leukaemia – transplantation for myelodysplastic syndrome – transplantation in acute lymphoid leukaemia – transplantation in non-Hodgkin lymphomas – transplantation for myelofibrosis with myeloid mataplasia – transplantation for chronic lymphatic leukaemia – transplantation for severe aplastic anaemia

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