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Vitamin D and neurological diseases


Authors: J. Polívka 1;  J. Polívka jr. 2;  M. Peterka 1;  V. Rohan 1;  P. Ševčík 1;  O. Topolčan 3
Authors‘ workplace: Neurologická klinika Lékařské fakulty UK a FN Plzeň, přednosta MUDr. Jiří Polívka, CSc. 1;  Fakulta aplikovaných věd Západočeské univerzity Plzeň, děkan doc. Ing. František Vávra, CSc. 2;  Oddělení nukleární medicíny FN Plzeň, úsek imunoanalýzy, přednosta MUDr. Dagmar Slípková 3
Published in: Vnitř Lék 2012; 58(5): 393-395
Category: Appendix: Vitamin D

Overview

We provide an overview of the association between vitamin D and some neurological diseases where the correlation has repeatedly been described. The majority of literature refers to cerebrovascular diseases, followed by multiple sclerosis and cognitive disorders. Vitamin D hypovitaminosis might be associated with the diseases directly or it might contribute to the disease risk factors (typically in cerebrovascular events). Vitamin D hypovitaminosis may also play a role in patients with residual functional involvement due to a neurological disorder (movement disorders, lack of self-sufficiency) and worsen functional status owing to muscle weakness, instability and falls.

Key words:
vitamin D – cerebrovascular disorders – multiple sclerosis – cognitive disorders


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