Survival of patients after TIPS in the University Hospital Hradec Kralove

Czech version

Authors: Š. Šembera ¹; V. Jirkovský ²; T. Fejfar ²; V. Šafka ²; O. Renc ³; J. Raupach ³; V. Chovanec ³; Miroslav Lojík ³; A. Krajina ³; P. Hůlek ²
Authors‘ workplace: Lékařská fakulta UK Hradec Králové, děkan prof. MUDr. RNDr. Miroslav Červinka, CSc. ¹; II. interní klinika Lékařské fakulty UK a FN Hradec Králové, přednosta prof. MUDr. Jaroslav Malý, CSc. ²; Radiologická klinika Lékařské fakulty UK a FN Hradec Králové, přednosta prof. MUDr. Pavel Eliáš, CSc. ³
Published in: Vnitř Lék 2011; 57(12): 1038-1044
Category: 70th birthday of prof. MUDr. Petr Dítě, DrSc.

Overview

Aim:
To analyze survival of patients after TIPS (transjugular intrahepatic portosystemic shunt).

Patient sample and methodology:
Between September 1992 and August 2010, TIPS was created in 848 patients of the University Hospital Hradec Kralove. These patients were divided into groups. Survival was analyzed using Kaplan-Meier survival curves. Differences between groups were evaluated using log-rank test.

Results:
Ten percent of patients do not survive one month after TIPS, 40% of patients survive 5 years and 20% of patients survive 10 years. There were statistically significant differences between groups divided according to Child-Pugh classification (A vs B p = 0.0053; B vs. C p < 0.0001), indication for surgery [prevention of bleeding recurrence differed from refractory ascites (p = 0.0001) and the indication to stop acute bleeding (p = 0.026)]; aetiology of the liver disease [patients with alcoholic cirrhosis differed from patients with Budd-Chiari syndrome (p < 0.0001) and from patients with chronic viral hepatitis (p = 0.024)].

Conclusion:
Survival of patients after TIPS is influenced by Child-Pugh score, indication and aetiology of the liver disease.

Key words:
transjugular intrahepatic portosystemic shunt – liver disease – Child-Pugh score – indication

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