Neuroendocrine tumours of the appendix

Czech version

Authors: O. Louthan
Authors‘ workplace: Ambulance pro neuroendokrinní nádory IV. interní kliniky 1. lékařské fakulty UK a VFN Praha, přednosta prof. MU Dr. Aleš Žák, DrSc.
Published in: Vnitř Lék 2009; 55(11): 1051-1055
Category: Reviews

Overview

According to WHO, neuroendocrine tumors of the appendix (appendiceal carcinoids) are defined as 1. well‑differentiated endocrine tumors with benign or uncertain behavior, 2. well‑differentiated endocrine carcinoma and 3. goblet cell carcinoma. These tumors are usually diagnosed incidentally during appendectomy. Carcinoid syndrome is rare in appendiceal carcinoid. Tumor size greater than 2 cm is the most important parameter for prognosis. Most patients are cured by appendectomy (appendiceal tumors ≤ 2 cm), tumors with a diameter > 2 cm should be managed by right hemicolectomy.

Key words:
goblet cell carcinoid – hemicolectomy – neuroendocrine tumor – WHO classification

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