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„Unknown” cause of the onset and recurrence of venous thromboembolism


Authors: P. Ďulíček 1;  L. Vodičková 2;  J. Malý 1;  M. Pecka 1;  M. Beránek 3
Authors‘ workplace: Oddělení klinické hematologie II. interní kliniky Lékařské fakulty UK a FN, Hradec Králové, přednosta prof. MUDr. J. Malý, CSc. 1;  I. interní klinika Lékařské fakulty UK a FN, Hradec Králové, přednosta prof. J. Vojáček, CSc. 2;  Oddělení klinické biochemie Lékařské fakulty UK a FN, Hradec Králové, přednosta prof. MUDr. V. Palička, CSc. 3
Published in: Vnitř Lék 2006; 52(1): 87-88
Category: Case Report

Overview

We reported the case of 61 years old man with the first episode of massive pulmonary embolism at the age of 54 without the proper explanation of the cause. Thrombocythaemia was manifested after the dismissal from the hospital but the origin of this condition was not clarified. Essential thrombocythaemia was diagnosed after the recurrence of venous thromboembolism and that is the explanation for thrombophilic condition in this patient. The patient is without problems and signs of recurrent venous thromboembolism after the achievement of the complete remission of myeloproliferative disease and well - managed of anticoagulation therapy.

Key words:
venous thromboembolism - pulmonary embolism - essencial thrombocythaemia


Sources

1. Bertina RM. Molecular risk factors for thrombosis. Thromb Haemost 1999; 82: 601-609.

2. Elliott MA, Tefferi A. Thrombosis and haemorrhage in polycythaemia vera and essential thrombocythaemia. Brit J of Haematol 2005; 128: 275-290.

3. Penninga E, Jensen BA, Hansen PB. Anagrelide treatment in 52 patients with chronic myeloproliferative disease. Clinical and Laboratory Haematology 2004; 26: 335-340.

Labels
Diabetology Endocrinology Internal medicine

Article was published in

Internal Medicine

Issue 1

2006 Issue 1

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