Migraeflux in acute treatment of migraine

Czech version

Authors: J. Mastík; I. Novotná
Authors‘ workplace: I. neurologická klinika Lékařské fakulty MU a FN u sv. Anny, Brno, přednosta prof. MUDr. Ivan Rektor, CSc.
Published in: Vnitř Lék 2005; 51(9): 984-987
Category: Original Contributions

Overview

Relatively large portion of migraine patients with and without aura may be classified according to MIDAS score into the groups I and II. In accordance with the method of stratified treatment it is recommended to use nonspecific combined antimigrainous agents during paroxysms in groups I and II. Authors demonstrated good tolerability and satisfactory efficacy of Migraeflux preparation (paracetamol with dimenhydrinate) both in the alleviation of headache intensity and in the action on accompanying symptoms (nausea, vomiting, photophobia and phonophobia). They noted also relatively low incidence of recurrence of migrainous paroxysms and adverse effects, which universally were of mild degree.

Key words:
migraine – acute treatment – stratified treatment – MIDAS

Sources

1. Allais G, De Lorenzo C, Airola G et al. Il dexketoprofene trometamolo nel trattamento dell´attacco acuto di emicrania. Minerva Med 2000; 91: 153-159.

2. Dahlof GGH, Hargreaves RJ. Pathophysiology and pharmacology of migraine. Is there a place for antiemetics in future treatment strategie? Cephalalgia 1998; 18: 593-604.

3. Doležil D, Doležal T. Moderní terapie migrény naratriptanem. Souč Klin Pr 2003; 3: 13-14.

4. Ferrari MD, Saxena PR. 5-HT1 receptors in migraine pathophysiology and treatment. European Journal of Neurology 1995; 2: 5-21.

5. Lipton RB, Stewart WF, Stone AM et al. Stratified care vs. step care strategies for migraine. The disability in strategies of care (DISC) study: a randomized trial. JAMA 2000; 284: 2599-2605.

6. Pfaffenrath V, Scherzer S. Analgesics and NSAIDs in the treatment of the acute migraine attack. Cephalalgia 1995; 15: 14-20.

7. Tfelt-Hansen P, Henry P, Mulder LJ et al. The effectiveness of combined oral lysine acetylsalicylate end metoclopramide compared with oral sumatriptan for migraine. Lancet 1995; 346: 923-926.

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Article was published in

Internal Medicine

2005 Issue 9