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Unexpected course of anti Xa activity after suicidal ingestion of rivaroxaban in an elderly patient


Authors: Hana Matějovská Kubešová 1;  Ondřej Výška 1;  Miroslav Penka 2;  Ondřej Ludka 1
Authors‘ workplace: Klinika interní, geriatrie a praktického lékařství LF MU a FN Brno 1;  Interní hematologická a onkologická klinika LF MU a FN Brno 2
Published in: Geriatrie a Gerontologie 2022, 11, č. 2: 95-98
Category:

Overview

The authors present a description of the course of a suicidal attempt in an elderly patient with mixed medication, including up to 12 tablets of rivaroxaban with a strength of 20 mg. Monitoring of anti-Xa activity showed its delayed onset compared to the manufacturer‘s data and clinical experience to date. The discussion considers the potential to influence the pharmacokinetics and pharmacodynamics of rivaroxaban with other medications and ethanol used concomitantly.

Keywords:

pharmacodynamics – rivaroxaban – anti Xa – suicidal attempt


Sources

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Geriatrics General practitioner for adults Orthopaedic prosthetics
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