Indapamide induced hyponatremia in an 83 year old patient
Authors:
H. Lacmanová; T. Richter; E. Topinková
Published in:
Geriatrie a Gerontologie 2018, 7, č. 1: 40-43
Category:
Case Reports
Overview
Hyponatremia is one of the most common electrolyte disorders in old age. As age advances the occurrence of hyponatremia risk factors increases. Thiazide and thiazide-like diuretics and antidepressants belong to drug classes with the highest incidence of adverse drug reaction – hyponatremia. In the case study we present an 83 years old female with indapamide-induced severe symptomatic hyponatremia with hypoosmolar hypovolemia which led to hospitalization. In thorough diagnostic process we were able to identify several other factors predisposing to hyponatremia while on diuretics – concomitant treatment with SSRI, acute infection, diabetes mellitus, chronic malnutrition. Treatment of hyponatremia – mainly stopping hyponatremia-inducing drugs, re-hydration with isoosmolar fluids, correction of hypomagnesemia, antibiotic treatment of infection led to clinical status improvement and increase of S-Na values. However, even after 4 weeks of treatment serum – Na concentrations did not return to the normal range.
KEYWORDS:
drug-induced hyponatremia – elderly – case study
Sources
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Labels
Geriatrics General practitioner for adults Orthopaedic prostheticsArticle was published in
Geriatrics and Gerontology
2018 Issue 1
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