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A pharmacotherapy of nursing home residents.


Authors: Mgr. Stanislava Kalafutová 1;  Mgr. Hana Šulcová 2;  MUDr. Božena Jurašková;  Ph. D 3;  prof. RNDr. Jiří Vlček, CSc. 4
Authors‘ workplace: Katedra sociální a klinické farmacie FaF UK Hradec Králové 1;  Nemocniční lékárna FN Motol, Praha 2;  III. interní gerontometabolická klinika LF UKa FN Hradec Králové 3;  Katedra sociální a klinické farmacie FaF UKHradec Králové 4
Published in: Geriatrie a Gerontologie 2014, 3, č. 2: 65-70
Category: Original Article/Study

Overview

Polypharmacy and the use of inappropriate medications in the elderly are a common cause of adverse drug reactions. Residents of nursing homes are more sensitive to poly-drug use and potential adverse drug reactions than community-dwelling seniors. The aim of this cross-sectional study was analysis of the pharmacotherapy in the nursing homes residents, focusing on the analysis of potentially in-appropriate medications in the elderly (using STOPP criteria) and drug interactions (using databases AISLP and software Micromedex). Medical information and demographic data were collected since February to May 2012. Statistical software MS Excel 2007 was used for statistical analyses.

The analysis was conducted in two nursing homes in Prague and Central region of the Czech Republic. Fifty eight residents aged 65 years and older were participated in the study. The mean age was 82 years, 74 % were female. Respondents were taking 8.9 prescription drugs, 1.2 non-prescription drugs and 0.6 dietary supplements per a capita. Potential drug interactions occurred in 86 % of respondents. Serious and very serious interactions occurred in 8.6% of respondents. 65 % of respondents were prescribed potentially inappropriate medicines.

The incidence of drug interactions among the nursing home residents is very high as well as the prescription of potentially inappropriate medicines.

Keywords:
nursing homes – pharmacotherapy of seniors – inappropriate medications in the elderly – drug interactions


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