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The prevalence of asymptomatic individuals with high risk of cardiovascular disease in the Czech population and their adherence to primary prevention targets


Authors: O. Mayer jr. 1;  R. Cífková 2;  J. Filipovský 1;  J. Seidlerová 1;  D. Slezák 1;  J. Střížová 1;  P. Vaněk 1;  P. Wohlfart 2;  J. Jeschke 1
Authors‘ workplace: Univerzita Karlova v Praze Lékařská fakulta a Fakultní nemocnice, Plzeň II. Interní klinika Přednosta: prof. MUDr. Jan Filipovský, CSc. 1;  Institut klinické a experimentální medicíny, Praha Pracoviště preventivní kardiologie Přednosta: prof. MUDr. Renata Cífková, CSc. 2
Published in: Prakt. Lék. 2010; 90(4): 230-234
Category: Of different specialties

Overview

Asymptomatic individuals with increased risk of cardiovascular disease (CVD) are a priority for prevention immediately after patients with established CVD. We aimed to establish the prevalence of asymptomatic high-risk subjects in the Czech population and to evaluate the adherence to primary prevention targets. The study looked at a general population based sample of 616 subjects (mean age 47.2 years). The overall 10 years absolute risk of a fatal vascular event was estimated using SCORE function localized for Czech population.

In total, 24.8 % of the subjects were at high-risk because of SCORE ≥ 5 % or were already treated with cardiovascular medication (antihypertensives or lipid-lowering drugs). Using a projection of current risk into 60 years of age, the prevalence of high-risk individuals increased to 46.9 %. In addition, 8.5 % reported a manifestation of CVD or were diabetic. In asymptomatic high-risk individuals, 29.4 % were obese, 52.2 % had increased waist circumference and 51.6 % were active smokers. The proportion of patients with raised blood pressure was 37.4 %, while 70.9 % had hypercholesterolemia; 11.8 % of subjects showed increased fasting glycaemia.

In conclusion, in our study we found a high prevalence of asymptomatic individuals with increased risk of CVD, and that the therapeutic control of individual risk factors is far from optimal.

Key words:
asymptomatic high-risk, SCORE, primary prevention, guidelines; adherence.


Sources

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