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Ankle-brachial indices and risk of cardiovascular complications


Authors: L. Válková;  E. Leichterová;  J. Válek
Authors‘ workplace: Institut pro vzdělávání lékařů ve zdravotnictví, Praha ;  Ředitel: MUDr. Zdeněk Hadra ;  Katedra všeobecného lékařství
Published in: Prakt. Lék. 2008; 88(4): 220-223
Category: Of different specialties

Overview

Aim:
the aim of the study was to verify the importance of using the ankle-brachial index for the prediction of cardiovascular complications in a three year pilot study of middle-aged men.

Material and methods:
A cohort of 442 males, followed in the consulting rooms of 14 general practices, was enrolled. Ankle-brachial index assessed with hand held continuous Doppler ultrasound for the measurement of blood pressure was calculated from the left (ABS), right (ABD) and both legs (ABI) and related to the arm pressures. Cumulative incidence of all signs of disease progression (invasive intervention on the peripheral arteries, coronary arteries, myocardial infarction and cerebrovascular events) occurring between years 2001–2004 was analyzed.

Results:
Mean ankle-brachial index ranged from 1.10 to 1.08 on either leg. Decreased values (<0.9) were found from 10.6 % males (ABI) to 12.4% (ABD). Cardiovascular complications were encountered in 32 men (7.3 %). Their ankle brachial indices were highly significantly decreased as compared with those of men without complications.

Conclusions:
Statistically significant relationship between cardiovascular complications and ankle-brachial indices were found even taking into account the age, blood pressure and symptoms of the metabolic syndrome. Decreased ankle-brachial index may contribute to the prediction of cardiovascular risk of middle aged men with a low to moderate risk, which might improve prevention in general practice.

Key words:
Ankle-brachial index, myocardial infarction, cardiovascular complications, prevention, primary care.


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