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Frequency of the Leiden Mutation Factor V in Women with Venous Thrombosis Hospitalized at the Cardiological Department in 1997-2000


Authors: Lepší P.';  J. Balázs 2;  R. Hoffmann 2;  B. Rypáčková 3;  Skalníková V.';  Niederle P.'
Authors‘ workplace: (Kardiologické oddělení Nemocnice Na Homolce, Praha, přednosta doc. MUDr. P. Niederle, DrSc. 20ddělení klinické biochemie a hematologie Nemocnice Na Homolce, Praha, přednosta prof. MUDr. J. Hyánek DrSc. 3I. interní klinika Všeobecné fakultní nemocnice, Pr
Published in: Prakt. Lék. 2002; (1): 9-10
Category:

Overview

The authors investigated the pozitivity ofthe Leiden mutation faktor V in 49 women hospitalized at their department with venous thrombosis. Examination for the presence of Leiden faktor V was made in 19 patients. A positive finding was recorded in 7 (i.e. 36.8%), predominantly with a proximal type of thrombosis of the veins of the lower extremities and pelvis. Of the mentioned seven patients six used hormonal contraception.

Key words:
thrombophilia - Leiden mutation faktor V - venous thrombosis.

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