Liver transplantation for acute liver failure

Czech version

Authors: E. Kieslichová ^1,2
Authors‘ workplace: Klinika anesteziologie, resuscitace a intenzivní péče, Institut klinické a experimentální medicíny, Praha 2 1. LF Univerzity Karlovy, Praha ¹
Published in: Gastroent Hepatol 2024; 78(2): 95-100
Category: Hepatology
doi: https://doi.org/10.48095/ccgh202495

Overview

Acute liver failure is a rare, highly devastating, potentially reversible condition characterised by the sudden onset of severe liver dysfunction in individuals without pre-existing liver disease and with a poor prognosis. In recent decades, advances in the diagnosis of the disease, a better understanding of its pathophysiology and the development of supportive care have improved the prognosis of patients with acute liver failure. However, despite the success of conservative therapy, urgent liver transplantation remains the only chance of survival for a large proportion of patients with acute liver failure. Early diagnosis of the disease, implementation of supportive care and identification of patients indicated for urgent liver transplantation are essential measures in the management of patients with acute liver failure.

Keywords:

acute liver failure – transplantation – supportive therapy – prognostic criteria

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ORCID autorky

E. Kieslichová 0000-0002-3930-623X.

Doručeno/Submitted: 28. 2. 2024

Přijato/Accepted: 13. 3. 2024

doc. MUDr. Eva Kieslichová, Ph.D.

Klinika anesteziologie, resuscitace a intenzivní péče

Institut klinické a experimentální medicíny

Vídeňská 1958/9

14000 Praha 4

evki@ikem.cz