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Autoimmune hepatitis after vaccination against COVID-19


Authors: V. Pítová 1;  J. Šperl 1;  P. Taimr 1;  O. Fabián 2,3;  T. Miřejovský 2;  L. Janoušek 4;  J. Chlupáč 4,5;  J. Špičák 1;  S. Fraňková 1
Authors‘ workplace: Klinika hepatogastroenterologie IKEM, Praha 1;  Pracoviště klinické a transplantační patologie IKEM, Praha 2;  Ústav patologie a molekulární medicíny 3. LF UK a FTN, Praha 3;  Klinika transplantační chirurgie IKEM, Praha 4;  Ústav anatomie 2. LF UK, Praha 5
Published in: Gastroent Hepatol 2023; 77(1): 52-56
Category: Hepatology: case report
doi: https://doi.org/10.48095/ccgh202352

Overview

In this case report, we present a 61-year-old patient admitted to the hospital because of tiredness and jaundice less than three weeks after vaccination against SARS-CoV-2 with the first dose of the Comirnaty vaccine (Pfizer/BioNTech). Based on the patient’s medical history, laboratory data, imaging methods and liver bio­psy, we dia­gnosed autoimmune hepatitis. The patient developed acute liver failure, and his liver function did not improve after corticosteroid administration. Therefore, the patient was enrolled in the waiting list and underwent a successful orthotopic liver transplantation.

Keywords:

vaccination – liver failure – COVID-19 – autoimmune hepatitis


Sources

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Labels
Paediatric gastroenterology Gastroenterology and hepatology Surgery

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Gastroenterology and Hepatology

Issue 1

2023 Issue 1

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