Enteropathy-Associated Non-Hodgkin T-Lymphoma as a Complication of Late Diagnosis of Celiac Disease in a Geriatric Patient
Authors:
P. Kružliak; E. Čičmancová
Authors‘ workplace:
Interné oddelenie NsP Bojnice
Published in:
Gastroent Hepatol 2010; 64(1): 7-11
Category:
Case Report
Overview
Enteropathy-associated non-Hodgkin T-lymphoma (EATL) is a tumor of intraepithelial T-lymphocytes of the small intestine with heterogeneous morphologic and clinical picture dependent on the degree of malignant transformation of the cells. This disease is presented as a malabsorption of mostly celiac origin which is supposed to be a precancerosis of this tumorous condition. The risk factors of the malignant complication development in patients with celiac are the gluten exposure time, celiac diagnosed in older patients and celiac refractory to the treatment. It is a serious disease with poor prognosis and high mortality. The authors present the clinical case of a patient who was diagnosed with celiac late and at a high age, complicated by the occurrence of EATL. This paper aims to point out the significance of celiac as precancerosis in patients of intermediate and older age and the alarming situation in celiac epidemiology related to the distinctive underdiagnosis of this disease in the population.
Key words:
celiac disease – precancerosis – enteropathy-associated non-Hodgkin T-lymphoma (EATL)
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Labels
Paediatric gastroenterology Gastroenterology and hepatology SurgeryArticle was published in
Gastroenterology and Hepatology
2010 Issue 1
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