Atrial fibrillation and metformin treatment
Authors:
Andrej Dukát 1; Milan Kriška 2; Ján Kyselovič 1; Juraj Payer 1
Authors‘ workplace:
V. interná klinika LF UK a UNB, Nemocnica Ružinov, Bratislava
1; Ústav farmakológie a klinickej farmakológie LF UK v Bratislave
2
Published in:
Forum Diab 2023; 12(1): 52-54
Category:
Overview
Last december Cell Reports Medicine brought significant paper, showing to metformin as a candidate drug for the patients with atrial fibrillation. Using the active comparator, a new design analysis of large-scale longitudinal electronic health record data, metformin use is significantly associated with a reduced risk of atrial fibrillation odds ratio: OR 0,48 (95% CI 0,36–0,54; p < 0,001) compared with standard treatment for diabetes. Metformin showed its benefits also among patients with infection of COVID-19. From its discovery one hundred years ago new data shows new indication for the clinical practice.
Sources
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Diabetology Endocrinology Internal medicineArticle was published in
Forum Diabetologicum
2023 Issue 1
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