Forensic Toxicological Implication of an Autopsy Case of Mixed Drug Overdose Involving Clomipramine, Chlorpromazine and Flunitrazepam
Authors:
Hiroshi Kinoshita 1; Minori Nishiguchi 1; Shogo Kasuda 1; Motonori Takahashi 1; Harumi Ouchi 1; Takako Minami 1; Kiyoshi Matsui 1; Takehiko Yamamura 1; Hiroyuki Motomura 2; Nao Ohtsu 1; Shie Yoshida 1; Nobuyuki Adachi 1; Takehiko Ohta 1; Motoo Komeda 1; Kiyoshi Ameno 3; Shigeru Hishida 1
Authors‘ workplace:
Department of Legal Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 66 -8501, Japan
1; Forensic Science Laboratory, Hyogo Prefectural Police Headquarters, 4-1, Shimoyamate -dori 5-chome, Chuo-ku, Kobe, 650-8510, Japan
2; Department of Forensic Medicine, Faculty of Medicine, Kagawa University, 1750-1 Miki, Kagawa, 761-0793, Japan
3
Published in:
Soud Lék., 53, 2008, No. 3, p. 28-30
Overview
A case of fatal poisoning involving clomipramine, chlorpromazine and flunitrazepam is presented. Quantitative toxicological analysis showed that the concentrations of clomipramine, chlorpromazine and 7-aminoflunitrazepam (a metabolite of flunitrazepam) in the femoral blood were 3.24 μg/ml, 0.36Ķg/ml and 0.61 μg/ml, respectively, and large amounts of drugs were also detected from the stomach contents. We concluded that the cause of death was due to the combined use of clomipramine, chlorpromazine and flunitrazepam.
Key words:
chlorpromazine – clomipramine – flunitrazepam – poisoning
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Labels
Anatomical pathology Forensic medical examiner ToxicologyArticle was published in
Forensic Medicine
2008 Issue 3
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