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Leiomyóm maternice s amianthoid-like vláknami


Authors: M. Zámečník 1;  P. Kaščák 2
Authors‘ workplace: Medicyt s. r. o., Laboratory Trenčín, Slovak Republic 1;  Department of Gynecology and Obstetrics, Faculty Hospital, Trenčín, Slovak Republic 2
Published in: Čes.-slov. Patol., 47, 2011, No. 3, p. 125-127
Category: Original Article

Overview

Prezentovaný je leiomyóm gynekologického typu s obsahom amianthoid-like vlákien. Šlo o 6-centimetrový tumor maternice u 46-ročnej ženy. Histologicky obsahoval celulárnu populáciu hladkosvalových buniek, v ktorej boli početné eozinofilné amianthoid-like vlákna. Morfologicky tumor napodobňoval palisádovaný “amiantoidný” myofibroblastóm. Immunofenotyp tumoru bol hladkosvalový, s expresiou h-caldesmonu, desmínu, alfa hladkosvalového aktínu a s negativitou CD10 a S100 proteinu. Nález amianthoid-like vlákien rozširuje morfologické spektrum leiomyómov a demonštruje fenotypické prekrývanie leiomyómu a palisádovaného myofibroblastómu.

Kľúčové slová:
maternica – amianthoid-like vlákna – leiomyóm gynekologického typu – palisádovaný myofibroblastóm


Sources

1. Suster S, Rosai J. Intranodal hemorrhagic spindle-cell tumor with “amianthoid” fibers. Report of six cases of a distinctive mesenchymal neoplasm of the inguinal region that simulates Kaposi’s sarcoma. Am J Surg Pathol 1989; 13: 347–357.

2. Weiss SW, Gnepp DR, Bratthauer GL. Palisaded myofibroblastoma. A benign mesenchymal tumor of lymph node. Am J Surg Pathol 1989; 13: 341–346.

3. Weiss SW, Goldblum JR. Benign tumors of smooth muscle. In: Enzinger and Weiss, eds. Soft Tissue Tumors (5th ed) Philadelphia, PA: Mosby Elsevier; 2008: 517–545.

4. Bagwan IN, Moss J, Fisher C, El-Bahrawy M. Amianthoid-like fibres in leiomyoma. Histopathology 2008; 53: 606–609.

5. Billings SD, Folpe AL,Weiss SW. Do leiomyomas of deep soft tissue exist? An analysis of highly differentiated smooth muscle tumors of deep soft tissue supporting two distinct subtypes. Am J Surg Pathol 2001; 25: 1134–1142.

6. Rao UN, Finkelstein SD, Jones MW. Comparative immunohistochemical and molecular analysis of uterine and extrauterine leiomyosarcomas. Mod Pathol 1999; 12: 1001–1009.

7. Dundr P, Povýšil C, Tvrdík D, Mára M. Uterine leiomyomas with inclusion bodies: an immunohistochemical and ultrastructural analysis of 12 cases. Pathol Res Pract 2007; 203: 145–151.

8. Kim DC, Kang TH, Kim MA, Jeon YK. Intranodal palisaded myofibroblastoma with desmin expression: a brief case report. Korean J Pathol 2009; 43: 263–265.

9. Eyden B, Chorneyko KA. Intranodal myofibroblastoma: study of a case suggesting smooth-muscle differentiation. J Submicrosc Cytol Pathol 2001; 33: 157- -163.

10. Michal M, Chlumská A, Povýšilová V. Intranodal “amianthoid” myofibroblastoma. Report of six cases: immunohistochemical and electron microscopical study. Pathol Res Pract 1992; 188: 199–204.

11. Oliva E, Clement PB, Young RH, Scully RE. Mixed endometrial stromal and smooth muscle tumors of the uterus: a clinicopathologic study of 15 cases. Am J Surg Pathol 1998; 22: 997–1005.

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Anatomical pathology Forensic medical examiner Toxicology

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Czecho-Slovak Pathology

Issue 3

2011 Issue 3

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