Authors: M. Zámečník 1; P. Kaščák 2 Authors‘ workplace: Medicyt s. r. o., Laboratory Trenčín, Slovak Republic 1; Department of Gynecology and Obstetrics, Faculty Hospital, Trenčín, Slovak Republic 2 Published in: Čes.-slov. Patol., 47, 2011, No. 3, p. 125-127 Category: Original Article
Prezentovaný je leiomyóm gynekologického typu s obsahom amianthoid-like vlákien. Šlo o 6-centimetrový tumor maternice u 46-ročnej ženy. Histologicky obsahoval celulárnu populáciu hladkosvalových buniek, v ktorej boli početné eozinofilné amianthoid-like vlákna. Morfologicky tumor napodobňoval palisádovaný “amiantoidný” myofibroblastóm. Immunofenotyp tumoru bol hladkosvalový, s expresiou h-caldesmonu, desmínu, alfa hladkosvalového aktínu a s negativitou CD10 a S100 proteinu. Nález amianthoid-like vlákien rozširuje morfologické spektrum leiomyómov a demonštruje fenotypické prekrývanie leiomyómu a palisádovaného myofibroblastómu.
Kľúčové slová: maternica – amianthoid-like vlákna – leiomyóm gynekologického typu – palisádovaný myofibroblastóm
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