#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Perforating Folliculitis. Case Report and Differential Diagnosis


Authors: K. Adamicová 1;  Ž. Fetisovová 2;  D. Výbohová 3;  Y. Mellová 3;  I. Chromej 2
Authors‘ workplace: Ústav patologickej anatómie 1;  Kožná klinika 2;  Ústav anatómie, Jesseniova lekárska fakulta v Martine, Univerzita Komenského v Bratislave 3
Published in: Čes.-slov. Patol., 45, 2009, No. 3, p. 75-78
Category: Original Article

Overview

A 26-year-old woman suddenly noticed an onset of disseminated papular exanthema during her institutional treatment for alcohol abuse. After 9 weeks of slowly progressive course a dermatologist was consulted, who suggested a diagnosis of pityriasis lichenoides. Skin biopsy revealed cystical enlargement of hair follicles that were filled up with keratinous and parakeratotic masses interspersed with particles of fragmented collagen. Numerous inflammatory cells were present within the lesion. Many focal perforations of infundibular epithelium draining a cellular debris were prominent. Severely disturbed follicles were engulfed by giant cell inflammatory infitrate containing remnants of collagen and elastic fibers. Considering all the histopathologic findings and clinical course, the case was finally diagnosed as perforating folliculitis, a distinct type from the family of perforating dermatoses.

Key words:
perforating folliculitis – perforating skin diseases


Sources

1. Ackermann, A. B.: Histologic diagnosis of inflammatory skin diseases. Philadelphia: Lea&Febiges, 1978, 833 s. 

2. Braun-Falco, O., Plewig, G., Wolf, H. H.: Dermatológia a venerológia. Martin: Vydavateľstvo Osveta, 2001, 1475 s. 

3. Brehmer-Anderson, E.: Dermatopathology. Berlin Heidelberg: Springer-Verlag, 2006, 245 s. 

4. Gilaberte, Y., Coscojuela, C., Vazquez, C., Rosello, R., Vera, J.: Perforating folliculitis associated with tumor necrosis factor- @ inhibitors administered for rheumatoid arthritis. British J. Dermatol., 156, 2007, s. 368–371.

5. Heilman, E. R., Friedman, R. J.: Degenerative diseases and perforating disorders. In: Elder, D., Elenitsas, R., Jaworsky, Ch., Johnson, B.: Leveręs histopathology of the skin. Philadelphia: Lippincott-Raven, 1997, s. 341–352.

6. Chang, P., Fernandez, V.: Acquired perforating disease: report of nine cases. Int. J. Dermatol. 32, 1993, s. 874–876.

7. Kempf, W., Hantschke, M., Kutzner, H., Burgdorf, W. H. C.: Dermatopathology. Würzburb: Steinkopf Verlag- Springer, 2008, 293 s. 

8. McKee, P. H., Calonje, E., Grantner, S. R.: Pathology of the skin. Vol. 1. London: Elsevier, 2005, 1683 s. 

9. Murphy G., F.: Dermatopathology. Philadelphia, Tokyo: W. B. Saunders, 1995, 489 s.

10. Neill, S. M., Vivier, A. W. P., Pembroke, A. R., Salisbury, J. R.: Phrynoderma and perforating folliculitis due to vitamin A deficiency in a diabetic. J Royal Soc. Med., 81, 1988, s. 171–172.

11. Nicholls, L.: Phrynoderma. A condition due to vitamin A deficiency. Indian Med Gaz., 68, 1933, s. 681–687.

12. Patterson, J. W.: Perforating folliculitis. http://emedicine.medscape.com /article/1071003-overview

13. Rubio, M., Herranz, P., Robayna, G., et al.: Perforating folliculitis: report of a case in an HIV-infected man. J. Am. Acad. Dermatol., 40, 1999, s. 300–302.

Labels
Anatomical pathology Forensic medical examiner Toxicology
Topics Journals
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#