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Sinonasal (angiocentric) T/NK Cell Lymphoma:Report of a Case With a -12-Year History Free ofRecurrent/Residual Disease and a SuddenDeterioration


Authors: L. Kren;  P. Depowski;  A. Wu *
Authors‘ workplace: Department of Pathology, Albany Medical College, Albany, New York, and *Department of Pathology, Stratton VA Medical Center, Albany, New York, U. S. A.
Published in: Čes.-slov. Patol., , 2002, No. 3, p. 113-116
Category:

Overview

This report describes a case involving a 78-year-old Caucasian male, whose medical history wassignificant for sinonasal (angiocentric) T/NK lymphoma, who was treated by surgery and radiationin 1988. After the treatment, the patient was apparently free of residual/recurrent disease fora period of 12 years. There was periodical clinical follow up including repeated biopsies. After thisperiod, the patient suffered from sudden deterioration of the health status with multiorgan involvementby the disease and he died. The diagnosis was confirmed by an autopsy.To our knowledge, this is the fifth reported case with extended survival (more than 12 years) freeof recurrent/residual disease after the initial treatment, in which the patients ultimately diedbecause of the disease. These findings suggest the importance of prolonged clinical follow-up inpatients with this diagnosis.

Key words:
sinonasal T/NK cell lymphoma - survival - clinical follow up

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Anatomical pathology Forensic medical examiner Toxicology
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