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Atypical Melanocytic Lesions: An Update

Czech version

Authors: L. Pock 1;  L. Drlík 2;  M. Důra 3
Published in: Čes-slov Derm, 98, 2023, No. 5, p. 235-252
Category: Reviews (Continuing Medical Education)

Overview

The genome of melanocytic lesions and its changes determinate their morphology and biological behaviour. Intermedial lesions are situated between nevi and melanomas, and they are difficult to be diagnosed. Melanocytomas have been separated from other atypical melanocytic lesions on the basis of new molecular-biological studies which have changed their classification. The article updates the topic of atypical melanocytic lesions from the point of diagnosis, therapy, and follow-up.

Sources
  1. ANDEA, A. A. Molecular testing for melanocytic tumors: a practical update. Histopathology, 2022, 80, p. 150–165.
  2. BENTON, S., ZHAO, J., ZHANG, B. et al. Impact of next-generation sequencing on interobsever agreement and diagnosis of spitzoid neoplasms. Am. J Surg Pathol, 2021, 45 (12), p. 1597–1605.
  3. BUSAM, K. J., GERAMI, P., SCOLYER, R. A. Pathology of Melanocytic Tumors. Available from: Elsevier eBooks+, Elsevier – OHCE, 2018.
  4. CERRONI, L., BARNHILL, R. L., ELDER, D. et al. Melanocytic tumors of uncertain malignant potential. Results of a tutorial held at the XXIX Symposium of the InternationalSociety of Dermatopathology in Graz, October 2008. Am J Sug Pathol, 2010, 34, p. 314–326.
  5. DONATTI, M., MARTÍNEK, P., STEINER, P. et al. Novel insight into the BAP1–inactivated melanocytic tumor. Modern Pathology, 2022, 35, p. 664–675.
  6. ELDER, D. E., BARNHILL, R. L., BASTIAN, B. C. et al. Melanocytic neoplasms, In: WHO Classification of Tumours Editorial Board: Skin Tumours. (Internet: beta version ahead of print. Lyon (France): International Agency for Research on Cancer; 2023. (WHO classification of tumours series, 5th ed.; vol. 12). Dostupné na www: https://tumourclassification.iarc. who.int/chapters/64.
  7. ELDER, D. E., MASSI, D., SCOLYER, R. A. et al. WHO Classification of Skin Tumours. 4th ed. Lyon: IARC. 2018. ISBN 978-92-832-2440-2.
  8. ELMORE, J. G., BARNHILL, R. L., ELDER, D. E. et. al. Pathologist´s diagnosis of invasive melanoma and melanocytic proliferations: observer accuracy and reproducibility study. BMJ, 2017, 28, p. 357.
  9. de la FOUCHARDIERE, A., BLOKX, W., van KEMPEN, L. C. et al. ESP, EORTC, and EURACAN Expert Opinion: practical recommendations for the pathologicaldiagnosis and clinical management of intermediate melanocytic tumors and rare related melanoma variants.Virchows Arch, 2021, 479 (1), p. 3–11.
  10. FRIEDMAN, E. B., DODDS, T. J., LO, S. et al. Correlation between surgical and histologic margins in melanoma wide excision specimens. Ann Surg Oncol, 2019, 26 (1), p. 25–32.
  11. HALPERN, A. C., GUERRY, D., ELDER, D. E. et al. Natural history of dysplastic nevi. J Am Acad Dermatol, 1993, 29 (1), p. 51–57.
  12. HOSLER, G. A., MURPHY, K. M. Ancillary testing for melanoma: current trends and practical considerations. Hum Pathol, 2023, S0046-8177 (23)00106–5.
  13. KUMAR, V., ABBAS, A. K., ASTER, J. C. Robbins Basic Pathology. 10th ed. Elsevier – Health Sciences Division. 2017, p. 281–283.
  14. LALLAS, A., KYRGIDIS, A., FERRARA, G. et al. Atypical Spitz tumours and sentinel lymph node biopsy: a systematic review. Lancet Oncol, 2014, 15 (4), p. 178–183.
  15. LEZCANO, C., JUNGBLUTH, A. A., NEHAL, K. S. et al. PRAME expression in melanocytic tumors. Am J Surg Pathol, 2018, 42, p. 1456–1465.
  16. LODHA, S., SAGGAR, S., CELEBI, J. T. et al. Discordance in the diagnosis of difficult melanocytic neoplasms in the clinical settings. J Cutan Pathol, 2008, 35 (4), p. 349–352.
  17. MARSDEN, J. R., NEWTON-BISHOP, J. A., BURROWS,vL. et al. Revised U. K. guidelines for the management of cutaneous melanoma. Br J Derm, 2010, 163, p. 238–256.
  18. MASSI, G., LeBOIT, P. E. Proliferative nodules in congenital and acquired nevi. In MASSI, G., LeBOIT, P. E. Histological diagnosis of nevi and melanoma (2nd ed.). Heidelberg, Springer; 2014, p. 97–112.
  19. MAURICHI, A., MICELI, R., PATUZZO, R. et al. Analysis of sentinel node biopsy and clinicopathologic features as prognostic factors in patients with atypical melanocytic tumors. J Natl Compr Canc Netw, 2020, 18 (10), p. 1327–1336.
  20. MOTAPARTHI, K., KIM, J., ANDEA, A. A. et al. TERT and TERT promoter in melanocytic neoplasms: Current concepts in pathogenesis, diagnosis, and prognosis. JCutan Pathol, 2020, 47 (8), p. 710–719.
  21. POCK, L., FIRKLE, T., DRLÍK, L. et al. Dermatoskopický atlas. 2. vyd., Praha: Phlebomedica, 2008, 149 s. ISBN 978-80-901298-5-6.
  22. POCK, L. Atypické melanocytární léze. Čes-slov Derm, 2013, 88 (3), p. 107–122.
  23. POCK, L., TRNKA, J., VOSMÍK, F. et al. Systematized progradient multiple combined melanocytic and blue nevus. Am JDermatopatol, 1991, 13 (3), p. 282–287.
  24. QUAN, V. L., PANAH, E., ZHANG, B. et al. The role of gene fusions in melanocytic neoplasms. J Cutan Pathol, 2019, 46 (11), p. 878–887.
  25. SHAIN, A. H., YEH, I., KOVALYSHYN, I. et al. The genetic evaluation of melanoma from precursor lesion. N Engl J Med, 2015, 373 (20), p. 1926–1936.
  26. TSAO, H., BEVONA, C., GOGGINS., W. et al. The transformation rate of moles (melanocytic nevi) into cutaneous melanoma: a population based estimate. Arch Dermatol, 2003, 139 (3), p. 282–288.
  27. TUCKER, M. A., HALPERN, A., HOLLY, E. A. et al. Clinically recognized dysplastic nevi. A central risk factor for cutaneous melanoma. JAMA, 1997, 277 (18), p. 1439–1444.
  28. VAREY, A. H. R., WILLIAMS, G. J., LO, S. N. et al. Clinical management of melanocytic tumours of uncertain malignant potential (MelTUMPs), including melanocytomas: A systematic review and meta-analysis. J Eur Acad Dermatol Venereol, 2023, 37 (5), p. 859–870.
  29. VERMARIËN-WANG, J., DOELEMAN, T., van DOORN, R. et al. Ambiguous melanocytic lesions: A retrospective cohort study of incidence and outcome ofmelanocytic tumor of uncertain malignant potential (MELTUMP) and superficial atypical melanocytic proliferationof uncertain significance (SAMPUS) in the Netherlands. J Am Acad Dermatol, 2023, 88 (3), p. 602–608.
  30. de WAAL, J. Skin tumour specimen shrinkage with excision and formalin fixation-how much and why: a prospective study and discussion of the literature. ANZ J Surg, 2021, 91 (12), p. 2744–2749.
  31. ZEMBOWICZ, A., CARNEY, J. A., MIHM, M. C. Pigmented epithelioid melanocytoma: a low-grade melanocytic tumor with metastatic potential indistinguishable from animal-type melanoma and epithelioid blue nevus. Am J Surg Pathol, 2004, 28 (1), p. 31–40.
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Czech-Slovak Dermatology

Issue 5
2023 Issue 5
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