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First Experiences with 1% Pimecrolimus Cream Therapy in Prevention of AtopicEczema Flares in Children


Authors: M. Salavec 1;  H. Bučková 2
Authors‘ workplace: Klinika nemocí kožních a pohlavních, Fakultní nemocnice Hradec Králové přednostka doc. MUDr. M. Nožičková, CSc. 2Dětské kožní oddělení, FN Brno - Dětská nemocnicepřednostka prim. MUDr. H. Bučková, Ph. D. 1
Published in: Čes-slov Derm, , 2004, No. 1, p. 3-7
Category:

Overview

First experiences withnewtopicalimmunomodulating therapy of atopic dermatitis in 40 childrenhas been analyzed by authors. Parameters of long-term efficacy and safety were evaluated during 1year double-blind, randomised clinical study following the introduction of 1% pimecrolimus creaminto the topical treatment of atopic dermatitis. The novel therapeutic regimen was effective and moresafe than current conventional therapy, reducing the incidence of flares of atopic dermatitis inchildren. The therapy did not influence the skin recal antigen tests. Pimecrolimus-based regimenpatients required substantially less corticosteroids than those in control groups.

Key words:
pimecrolimus - atopic dermatitis - topical treatment

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Labels
Dermatology & STDs Paediatric dermatology & STDs
Topics Journals
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