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The relation of rheumatic diseases and their treatment to clinical renal involvement


Authors: A. Klíčová 1;  P. Horák 1;  T. Tichý 2;  J. Zadražil 1
Authors‘ workplace: III. interní klinika – nefrologická, revmatologická a endokrinologická FN a LF UP, Olomouc 1;  Ústav klinické a molekulární patologie FN a LF UP, Olomouc 2
Published in: Čes. Revmatol., 23, 2015, No. 4, p. 133-145.
Category: Review Article

Overview

Number of rheumatic diseases manifest with involvement of renal and urinary system. Connective tissue diseases and vasculitides are often accompanied by glomerulonephritis. Involvement of renal interstitium is often present in connective tissue diseases such as certain forms of systemic lupus or Sjögren's syndrome, and vascular involvement typical for systemic sclerosis or antiphospholipid syndrome. Inflammatory diseases may also be accompanied by AA amyloidosis associa­ted with nephrotic syndrome and renal failure. Renal impairment occurs frequently in patients with hyperuricaemia. The effect of drugs used for treatment of rheumatic diseases on a kidney represents a separate chapter. On the other hand, even patients on dialysis often need to continue the treatment of rheumatic diseases. These questions are explored in the present review article.

Key words:
rheumatic diseases, renal involvement, hemodialysis, complications, specific isssues of the treatment


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