Inflammatory bowel diseases in pregnancy

Czech version

Authors: M. Andrášová ¹; A. Pařízek ¹; K. Lukáš ²
Authors‘ workplace: Gynekologicko porodnická klinika 1. LF UK a VFN, Praha, přednosta prof. MUDr. A. Martan, DrSc. ¹; IV. interní klinika – klinika gastroenterologie a hepatologie 1. LF UK a VFN, Praha, přednosta prof. MUDr. A. Žák, DrSc. ²
Published in: Ceska Gynekol 2020; 85(2): 144-148
Category:

Overview

Objective: To bring actual summary of pre and perinatal care of women with Crohn's disease and ulcerative colitis.

Design: Review.

Setting: Department of Gynaecology and Obstetrics, General Faculty Hospital and 1st Faculty of Medicine, Prague.

Methods: Review of articles.

Conclusion: Care of women with inflammatory bowel diseases should be placed in a specialised centre and management of pregnancy should be discussed by a multidisciplinary team included obstetrician, gastroenterologist, surgeon and nutritional specialist. All the possibilities in treatment of these women (except a few of them) are safe during the pregnancy and in the puerperium both for mother and fetus.

Keywords:

inflammatory bowel disease – IBD – pregnancy – biological therapy – Crohn

Sources

1. Beaulieu, DB., Kane, S. Inflammatory bowel disease in pregnancy. World J Gastroenterol, 2011, 17(22), p. 2696–2701.

2. Bortlik, M., Duricova, D., Machkova, N., et al. Impact of anti-tumor necrosis factor alpha antibodies administered to pregnant women with inflammatory bowel disease on long-term outcome of exposed children. Inflamm Bowel Dis, 2014, 20(3), p. 495–501.

3. Hashash, JG., Kane, S. Pregnancy and inflammatory bowel disease. Gastroenterol Hepatol, 2015,11(2), p. 96–102.

4. Huang, VW., Habal, FM. From conception to delivery: managing the pregnant inflammatory bowel disease patient. World J Gastroenterol, 2014, 20(13), p. 3495–3506.

5. Kapoor, D., Teahon, K., Wallace, SVF. Inflammatory bowel disease in pregnancy. Obstet Gynaecol, 2016, 18(3), p. 205–212.

6. Koželuhová, J., Baliha, K., Janská, E., et al. Terapie idiopatických střevních zánětů v graviditě. Inter Med pro praxi, 2015, 17(5), s. 218–222.

7. Lichtenstein, GR., Travis, S., Danese, S., et al. Budesonide MMX for the induction of remission of mild to moderate ulcerative colitis: a pooled safety analysis. J Crohns Colitis, 2015.

8. Mahadevan, U., Robinson, C., Bernasko, N., et al. Inflammatory bowel disease in pregnancy clinical care pathway: A report from the American gastroenterological association IBD parenthood project working group. Gastroenterology, 2019, 156(5), p.1508–1524.

9. Ng, SW., Mahadevan, U. My treatment approach to management of the pregnant patient with inflammatory bowel disease. Mayo Clin Proc, 2014, 89(3), p. 355–360.

10. Peppercorn, MA., Mahadevan, U. Patient education: Inflammatory bowel disease and pregnancy (beyond the basics). In Robson, KM., Waltham (Massachusetts): UpToDate, 2019, p. 1–10.

11. Schulze, H., Esters, P., Dignass, A. Review article: the management of Crohn‘s disease and ulcerative colitis during pregnancy and lactation. Aliment Pharmacol Ther, 2014, 40(9), p. 991–1008.

12. Yarur, A., Kane, SV. Update on pregnancy and breastfeeding in the era of biologics. Dig Liver Dis, 2013, 45(10), p. 787–794.

13. https://www.ouh.nhs.uk/patient-guide/leaflets/files/14054Pibd.pdf