Ovarian epithelial malignant tumors in adolescence
Authors:
Luboš Minář 1; Z. Ivanová 1; E. Jandáková 2
Authors‘ workplace:
Gynekologicko-porodnická klinika LF MU a FN, Brno, přednosta prof. MUDr. P. Ventruba, DrSc., MBA
1; Ústav patologie LF MU a FN, Brno, přednosta doc. MUDr. L. Křen, Ph. D.
2
Published in:
Ceska Gynekol 2014; 79(2): 98-102
Overview
Objective:
Ovarian epithelial malignant tumors in adolescence.
Design:
Literature review with case reports.
Setting:
Department of Gynaecology and Obstetrics, Faculty of Medicine at Masaryk´s University and Fakulty Hospital Brno.
Methods:
Literature review on ovarian epithelial malignant tumors in adolescence, their epidemiology, diagnosis and therapy with illustrative case reports.
Conclusion:
The ovarian epithelial malignant tumors in the adolescence represent rare group of these diseases according to the data from the National Cancer Registry. However, it is a very sensitive area of oncogynecology, that requires highly personalized approach and the cooperation with patient´s family. The ovarian epithelial malignant tumors in the age group of 15–19 years show some differences from these diseases of adults and older women. The differences concern the extent of the disease at the time of the diagnosis, the histopathological characteristics of the tumors and the proportion surgical therapy and chemotherapy. The diagnostic algorithm requires the cooperation with the colleagues from pediatric gynecology and oncology. Due to the occurrence of localizated stages and good tumor differentiation prevails the monotherapy presented the surgical treatment, especially in the form of the radical fertility-preserving procedures. The care of the patients should be concentrated into the oncogynecological centres.
Keywords:
ovarian epithelial malignant tumors, adolescence, fertility sparing surgical treatment, chemotherapy
Sources
1. Bajčiová, V. Epitelové nádory ovaria. In Bajčiová, V., Tomášek, J., Štěrba, J. Nádory adolescentů a mladých dospělých. Praha: Grada Publishing, 2011, s. 197–203.
2. Bleyer, WA., Viny, A., et al. Cancer in 15- to 29-year olds by primary site. Oncologists, 2006(11), p. 590.
3. Brown, J., Olson, T., et al. Malignancies of the ovary. Chapter 13. In Bleyer, WA., Barr, RD. Cancer in adolescents and young adults. Berlin: Springer-Verlag, 2007, p. 219–221.
4. Cibula, D., Petruželka, L., et al. Onkogynekologie. Praha: Grada Publishing, 2009, s. 503–508.
5. Dundr, P. Histopatologická klasifikace nádorů ženského genitálu. Mod Gynek Porod, 2007, 16(3), s. 509–510.
6. Fischerová, D. Ultrazvukové zobrazení benigních a maligních ovariálních nádorů. Mod Gynek Porod, 2007, 16(4), s. 752–754.
7. Motlík, K., Živný, J. Patologie v ženském lékařství. Praha: Grada, 2001, s. 550.
8. Poncelet, C., Fauvet, R., Boccara, J., et al. Recurrence after cystectomy for bordeline ovarian tumors: result of a French multicenter study, Ann Surg Oncol, 2006, 13, p. 565–571.
9. Silva, EG., Gerhenson, DM., Malpica, A., et al. The recurrence and the overall survival rates of ovarian serous borderline neoplasms with noninvasive implants in the time dependent. Am J Surg Pathol, 2006, 30(11), p. 1367–1370.
10. Stepanian, G., Cohn, DE. Gynecologic malignancies in adolescents. Adolesc Med Clin, 2004, 15(3), p. 549–558.
11. Tsai, JY., Saigo, PE., Brown, C., et al. Diagnosis, pathology, staging, treatment and outcome of epithelial ovarian neoplasia in patients age < 21 years. Cancer, 2001, 91(11), p. 2065–2070.
12. You, W., Dainty, LA., et al. Gynecologic malignancies in women aged less than 25 years. Obstet Gynecol, 2005, 105(6), p. 1405–1407.
13. http://www.onkogynekologie.com - Guideline C56 Epit 2013.
14. http://www.svod.cz
Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Czech Gynaecology
2014 Issue 2
Most read in this issue
- Role of prebioptic and bioptic methodsin the screening and diagnosis of cervical cancer
- Intrauterine fetal death syndrom: analysis of cases from 2008 to 2012 in Institute for the care of mother and child
- New views on the functional morphology of human clitoris
- Breech presentation – an analysis of resultsin one perinatal center