Comparison of prenatal ultrasound examination, post-mortem magnetic resonance imaging and autopsy (a case report – schizencephaly)
Authors:
M. Vaněčková 1; Z. Seidl 1,2; B. Goldová 3; I. Vítková 3; A. Baxová 4; P. Calda 5
Authors‘ workplace:
Radiodiagnostická klinika, odd MR, 1. LF UK a VFN, Praha, přednosta prof. MUDr. J. Daneš, CSc.
1; Vysoká škola zdravotnická, Praha, rektor prof. MUDr. Z. Seidl, CSc.
2; Ústav patologie, 1. LF UK a VFN, Praha, přednosta prof. MUDr. C. Povýšil, DrSc.
3; Ústav biologie a lékařské genetiky, 1. LF UK a VFN, Praha, přednosta doc. MUDr. M. Kohoutová, CSc.
4; Gynekologicko-porodnická klinika, 1. LF UK a VFN, Praha, přednosta prof. MUDr. A. Martan, DrSc.
5
Published in:
Ceska Gynekol 2009; 74(3): 225-228
Overview
Objective:
To improve prenatal diagnostic with a feedback of autopsy, complemented by post mortem magnetic resonance imaging (MRI). MRI is important for malformations of CNS, where autopsy can be insufficient.
Subject:
Case report.
Setting:
MR unit of the Department of radiology, Department of obstetrics and gynaecology and Department of pathology, 1st medical school, Charles University in Prague, General Teaching Hospital.
Subject and method:
To compare prenatal ultrasound, post mortem MRI and autopsy.
Conclusion:
Case report documented complementarity of all three method; full agreement in brain malformation type was found.
Key words:
post mortem MR, autopsy, ultrasound, schizencephaly.
Sources
1. Cohen, MC., Paley, MN., Giffiths, PD., et al. Less invasive autopsy: benefits and limitations of the use of magnetic resonance imaging in the perinatal postmortem. Pediatr Dev Pathol, 2008, 11, 1, p. 1-9.
2. Garel, C. MRI of the fetal brain. Berlin Heidelberg: Springer-Verlag, 2004, p. 267.
3. Granat, T., Farina, L., Faiella, A., et al. Familian schizencephaly associated with EMX2 mutation. Neurology, 1997, 48, 5, p. 1403-1406.
4. Hayashi, N., Tsutsumi, Y., Barkovich, AJ. Morphological features and associated anomalies of schizencephaly in the clinical population: detailed analysis of MR images. Neuroradiology, 2002, 44, 5, p. 418-427.
5. Karen, Y., Kennedy, AM., Frias, A., et al. Fetal schizencephaly: pre- and postnatal imaging with a review of the clinical manifestations. RadioGraphics, 2005, 25, p. 647-657.
6. Osborn, AG., Blaser, SI., Salzman, KL., et al. Diagnostic imaging brain. Utah, Salt Lake City: Amirsys Inc, 2004.
7. Sebire, NJ. Towards the minimally invasive autopsy? Ultrasound Obstet Gynecol, 2006, 28, p. 865-867.
8. Seidl, Z., Vaněčková, M. Magnetická rezonance hlavy, mozku a páteře. Praha: Grada 2007.
9. Whitby, EH., Paley, MNJ., Cohen, M., et al. Post-mortem fetal MRI: What do we learn from it? Eur J Radiol, 2006, 57, p. 250-255.
Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Czech Gynaecology
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